WormBase Tree Display for Variation: WBVar00275289
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WBVar00275289 | Name | Public_name | y9 | ||||||
---|---|---|---|---|---|---|---|---|---|
Sequence_details | SeqStatus | Pending_curation | |||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Strain (17) | |||||||||
Laboratory | TY | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00006962 | |||||||
Interactor (21) | |||||||||
Genetics | Mapping_data | In_multi_point | 1327 | ||||||
1328 | |||||||||
1329 | |||||||||
1330 | |||||||||
1331 | |||||||||
1336 | |||||||||
1337 | |||||||||
1583 | |||||||||
In_pos_neg_data | 3641 | ||||||||
7296 | |||||||||
7297 | |||||||||
7298 | |||||||||
Description | Phenotype | WBPhenotype:0000006 | Paper_evidence | WBPaper00053589 | |||||
Curator_confirmed | WBPerson15784 | ||||||||
WBPhenotype:0000065 | Paper_evidence | WBPaper00001077 | |||||||
WBPaper00001708 | |||||||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | All XO animals die as L1 larvae or younger. | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
XO animals die as embryos or small crumpled feminized L1 larvae with disorganized cellular structures. | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Recessive | Paper_evidence | WBPaper00001077 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | him-8(e1489); xol-1(y9) | Paper_evidence | WBPaper00001077 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000113 | Paper_evidence | WBPaper00001077 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | myo-2 and uvt-4 transcript levels in XO animals are reduced compared to wild-type controls, as assayed by a Northern blot. myo-2 and uvt-4 transcript levels in XX animals are similar to wild-type. | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | him-8(e1489) or him-5(e1490) | Paper_evidence | WBPaper00001077 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000583 | Paper_evidence | WBPaper00001077 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Animals segregate 3% XXX (Dumpy) progeny. | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Penetrance | Low | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Recessive | Paper_evidence | WBPaper00001077 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | him-8(e1489); xol-1(y9) | Paper_evidence | WBPaper00001077 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000718 | Paper_evidence | WBPaper00001077 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | XO animals employ the XX mode of dosage compensation. | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000743 | Paper_evidence | WBPaper00031121 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Animals exhibited reduced effectiveness of RNAi against some genes (mom-2, unc-22 and probably sdc-2). | Paper_evidence | WBPaper00031121 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000822 | Paper_evidence | WBPaper00053589 | |||||||
Curator_confirmed | WBPerson15784 | ||||||||
WBPhenotype:0000930 | Paper_evidence | WBPaper00001077 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Cells in some XO dying larvae adopt hermaphrodite fates, based on the presence of a HSN, coelomocytes in the hermaphrodite position and absence of characteristically male, large, B cells. | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Penetrance | Incomplete | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0006830 | PATO:0000460 | Paper_evidence | WBPaper00001077 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBbt:0003825 | PATO:0000460 | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBbt:0005751 | PATO:0000460 | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00001077 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | unc-32/+; him-5/dpy-21; flu-2 xol-1(y9)/0 | Paper_evidence | WBPaper00001077 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001025 | Paper_evidence | WBPaper00053589 | |||||||
Curator_confirmed | WBPerson15784 | ||||||||
WBPhenotype:0001572 | Paper_evidence | WBPaper00053589 | |||||||
Curator_confirmed | WBPerson15784 | ||||||||
Remark | Figure 3, hermaphrodite sex phenotype at 15 degrees Celsius; intersex phenotype at 20 degree Celsius; male sex phenotype at 25 degree Celsius | Paper_evidence | WBPaper00053589 | ||||||
Curator_confirmed | WBPerson15784 | ||||||||
Phenotype_not_observed | WBPhenotype:0000066 | Paper_evidence | WBPaper00001077 | ||||||
WBPaper00030931 | |||||||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | All XX animals are fully viable. | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
97% hermaphrodite viability (n=1251). | Paper_evidence | WBPaper00030931 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
XX animals viable, apparently WT hermaphrodites. | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Treatment | Embryos of 6 independent sets of progeny were counted. | Paper_evidence | WBPaper00030931 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Genotype | dpy-6(e14) | Paper_evidence | WBPaper00030931 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000136 | Paper_evidence | WBPaper00031121 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Transcript levels of her-1 were not elevated as assayed by qRT-PCR and normalized to nhr-1, whose expression is not affected by dosage compensation. | Paper_evidence | WBPaper00031121 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00031121 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000673 | Paper_evidence | WBPaper00001077 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Brood size with or without him-8(e1489) is normal. | Paper_evidence | WBPaper00001077 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00001077 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001410 | Paper_evidence | WBPaper00031121 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Assayed by staining XX embyos with anti-DPY-27 antibody. | Paper_evidence | WBPaper00031121 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00031121 | ||||
Curator_confirmed | WBPerson712 | ||||||||
Reference (21) | |||||||||
Method | Allele |