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WormBase Tree Display for Variation: WBVar00275289

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Name Class

WBVar00275289NamePublic_namey9
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
Strain (17)
LaboratoryTY
StatusLive
AffectsGeneWBGene00006962
Interactor (21)
GeneticsMapping_dataIn_multi_point1327
1328
1329
1330
1331
1336
1337
1583
In_pos_neg_data3641
7296
7297
7298
DescriptionPhenotypeWBPhenotype:0000006Paper_evidenceWBPaper00053589
Curator_confirmedWBPerson15784
WBPhenotype:0000065Paper_evidenceWBPaper00001077
WBPaper00001708
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RemarkAll XO animals die as L1 larvae or younger.Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
XO animals die as embryos or small crumpled feminized L1 larvae with disorganized cellular structures.Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
Phenotype_assayGenotypehim-8(e1489); xol-1(y9)Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
WBPhenotype:0000113Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
Remarkmyo-2 and uvt-4 transcript levels in XO animals are reduced compared to wild-type controls, as assayed by a Northern blot. myo-2 and uvt-4 transcript levels in XX animals are similar to wild-type.Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
Phenotype_assayGenotypehim-8(e1489) or him-5(e1490)Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
WBPhenotype:0000583Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
RemarkAnimals segregate 3% XXX (Dumpy) progeny.Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
PenetranceLowPaper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
Phenotype_assayGenotypehim-8(e1489); xol-1(y9)Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
WBPhenotype:0000718Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
RemarkXO animals employ the XX mode of dosage compensation.Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
WBPhenotype:0000743Paper_evidenceWBPaper00031121
Curator_confirmedWBPerson712
RemarkAnimals exhibited reduced effectiveness of RNAi against some genes (mom-2, unc-22 and probably sdc-2).Paper_evidenceWBPaper00031121
Curator_confirmedWBPerson712
WBPhenotype:0000822Paper_evidenceWBPaper00053589
Curator_confirmedWBPerson15784
WBPhenotype:0000930Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
RemarkCells in some XO dying larvae adopt hermaphrodite fates, based on the presence of a HSN, coelomocytes in the hermaphrodite position and absence of characteristically male, large, B cells.Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0006830PATO:0000460Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
WBbt:0003825PATO:0000460Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
WBbt:0005751PATO:0000460Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
Life_stageWBls:0000024PATO:0000460Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
Phenotype_assayGenotypeunc-32/+; him-5/dpy-21; flu-2 xol-1(y9)/0Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
WBPhenotype:0001025Paper_evidenceWBPaper00053589
Curator_confirmedWBPerson15784
WBPhenotype:0001572Paper_evidenceWBPaper00053589
Curator_confirmedWBPerson15784
RemarkFigure 3, hermaphrodite sex phenotype at 15 degrees Celsius; intersex phenotype at 20 degree Celsius; male sex phenotype at 25 degree CelsiusPaper_evidenceWBPaper00053589
Curator_confirmedWBPerson15784
Phenotype_not_observedWBPhenotype:0000066Paper_evidenceWBPaper00001077
WBPaper00030931
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RemarkAll XX animals are fully viable.Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
97% hermaphrodite viability (n=1251).Paper_evidenceWBPaper00030931
Curator_confirmedWBPerson712
XX animals viable, apparently WT hermaphrodites.Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Phenotype_assayTreatmentEmbryos of 6 independent sets of progeny were counted.Paper_evidenceWBPaper00030931
Curator_confirmedWBPerson712
Genotypedpy-6(e14)Paper_evidenceWBPaper00030931
Curator_confirmedWBPerson712
WBPhenotype:0000136Paper_evidenceWBPaper00031121
Curator_confirmedWBPerson712
RemarkTranscript levels of her-1 were not elevated as assayed by qRT-PCR and normalized to nhr-1, whose expression is not affected by dosage compensation.Paper_evidenceWBPaper00031121
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000003PATO:0000460Paper_evidenceWBPaper00031121
Curator_confirmedWBPerson712
WBPhenotype:0000673Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
RemarkBrood size with or without him-8(e1489) is normal.Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00001077
Curator_confirmedWBPerson712
WBPhenotype:0001410Paper_evidenceWBPaper00031121
Curator_confirmedWBPerson712
RemarkAssayed by staining XX embyos with anti-DPY-27 antibody.Paper_evidenceWBPaper00031121
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000003PATO:0000460Paper_evidenceWBPaper00031121
Curator_confirmedWBPerson712
Reference (21)
MethodAllele