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WormBase Tree Display for Variation: WBVar00249698

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Name Class

WBVar00249698NamePublic_nametm666
HGVSgCHROMOSOME_V:g.19050641_19051121delinsTTTA
Sequence_detailsSMapS_parentSequenceY39B6A
Flanking_sequencescggcgtgctgtgaagccaagaaggcggtgttgaagcttaacacgatttgaggcagtttcc
Mapping_targetY39B6A
Source_location7CHROMOSOME_V1905064019051122Inferred_automaticallyNational_Bioresource_Project
Type_of_mutationInsertionTTTA
Deletion
PCR_producttm666_external
tm666_internal
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
LaboratoryFX
AuthorMitani S
DB_infoDatabaseNational_Bioresource_Projectseq666
NBP_allele
StatusLive
AffectsGeneWBGene00000214
TranscriptY39B6A.20.1VEP_consequencecoding_sequence_variant,5_prime_UTR_variant
VEP_impactMODIFIER
cDNA_position?-112
CDS_position?-112
Protein_position?-38
Exon_number1/1
IsolationMutagenTMP/UV
GeneticsMapV
DescriptionPhenotypeWBPhenotype:0000324Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
RemarkComment from Dr. N. Tavernarakis to the National Bioresource Project of Japan: slightly shorter.Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
Laboratory_evidenceIR
WBPhenotype:0000547Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
RemarkComment from Dr. N. Tavernarakis to the National Bioresource Project of Japan: starved appearance.Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
Laboratory_evidenceIR
WBPhenotype:0000673Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
RemarkComment from Dr. N. Tavernarakis to the National Bioresource Project of Japan: less progeny at 25C.Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
Laboratory_evidenceIR
Phenotype_assayTemperature25Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
WBPhenotype:0001507Paper_evidenceWBPaper00049138
Person_evidenceWBPerson18666
Curator_confirmedWBPerson18666
Remarkmutants are tolerant to Cry6Aa proteinPaper_evidenceWBPaper00049138
Person_evidenceWBPerson18666
Curator_confirmedWBPerson18666
Phenotype_not_observedWBPhenotype:0000062Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
RemarkClassified as homozygous viable by the National Bioresource Project of Japan.Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
Laboratory_evidenceFX
WBPhenotype:0000531Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
RemarkComment from Dr. N. Tavernarakis to the National Bioresource Project of Japan: normal development.Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
Laboratory_evidenceIR
WBPhenotype:0000643Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
RemarkComment from Dr. N. Tavernarakis to the National Bioresource Project of Japan: normal locomotion.Person_evidenceWBPerson7743
Curator_confirmedWBPerson712
Laboratory_evidenceIR
ReferenceWBPaper00049138
Remark92584/92585-TTTA-93065/93066 (481 bp deletion + 4 bp insertion)
This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use.Paper_evidenceWBPaper00041807
MethodNBP_knockout_allele