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WormBase Tree Display for Gene: WBGene00000214

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Name Class

WBGene00000214EvidenceCGC_data_submission
SMapS_parentSequenceY39B6A
IdentityVersion1
NameCGC_nameasp-1Person_evidenceWBPerson184
Sequence_nameY39B6A.20
Molecular_nameY39B6A.20
Y39B6A.20.1
CE21681
Other_nameY39B6B.gCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y39B6A.20Accession_evidenceNDBBX284605
Public_nameasp-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classasp
Allele (35)
StrainWBStrain00001516
RNASeq_FPKM (74)
GO_annotation (18)
Ortholog (57)
Paralog (18)
Structured_descriptionConcise_descriptionasp-1 encodes a homolog of cathepsin D aspartic protease; it is transcribed exclusively in intestinal cells of the late embryo and early larvae and is not observed in older larvae or adults; ASP-1 is dispensable for neuronal degeneration.Paper_evidenceWBPaper00004299
WBPaper00005513
Curator_confirmedWBPerson324
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Located in cytoplasm and external side of apical plasma membrane. Expressed in intestinal cell and intestine. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human PGC (progastricsin) and REN (renin).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (17)
Molecular_infoCorresponding_CDSY39B6A.20
Corresponding_transcriptY39B6A.20.1
Other_sequence (155)
Associated_feature (18)
Experimental_infoRNAi_result (17)
Expr_pattern (12)
Drives_constructWBCnstr00002373
WBCnstr00010076
WBCnstr00022452
WBCnstr00037658
Construct_productWBCnstr00010076
WBCnstr00022452
WBCnstr00037658
AntibodyWBAntibody00000301
Microarray_results (20)
Expression_cluster (284)
Interaction (49)
WBProcessWBbiopr:00000134
Map_infoMapVPosition18.5005Error0.138896
PositivePositive_cloneY39B6AInferred_automaticallyFrom sequence, transcript, pseudogene data
Y39B6B
Mapping_dataMulti_point4527
5346
Pseudo_map_position
Reference (31)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene