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WormBase Tree Display for Gene: WBGene00000214

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Name Class

WBGene00000214EvidenceCGC_data_submission
SMapS_parentSequenceY39B6A
IdentityVersion1
NameCGC_nameasp-1Person_evidenceWBPerson184
Sequence_nameY39B6A.20
Molecular_nameY39B6A.20
Y39B6A.20.1
CE21681
Other_nameY39B6B.gCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y39B6A.20Accession_evidenceNDBBX284605
Public_nameasp-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classasp
Allele (35)
StrainWBStrain00001516
RNASeq_FPKM (74)
GO_annotation (18)
Ortholog (57)
Paralog (18)
Structured_descriptionConcise_descriptionasp-1 encodes a homolog of cathepsin D aspartic protease; it is transcribed exclusively in intestinal cells of the late embryo and early larvae and is not observed in older larvae or adults; ASP-1 is dispensable for neuronal degeneration.Paper_evidenceWBPaper00004299
WBPaper00005513
Curator_confirmedWBPerson324
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Located in cytoplasm and external side of apical plasma membrane. Expressed in intestinal cell and intestine. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human PGC (progastricsin) and REN (renin).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (17)
Molecular_infoCorresponding_CDSY39B6A.20
Corresponding_transcriptY39B6A.20.1
Other_sequence (155)
Associated_feature (18)
Experimental_infoRNAi_result (17)
Expr_pattern (12)
Drives_constructWBCnstr00002373
WBCnstr00010076
WBCnstr00022452
WBCnstr00037658
Construct_productWBCnstr00010076
WBCnstr00022452
WBCnstr00037658
AntibodyWBAntibody00000301
Microarray_results (20)
Expression_cluster (284)
InteractionWBInteraction000029754
WBInteraction000136795
WBInteraction000136876
WBInteraction000136885
WBInteraction000136904
WBInteraction000140859
WBInteraction000140874
WBInteraction000144237
WBInteraction000144254
WBInteraction000144261
WBInteraction000144267
WBInteraction000144275
WBInteraction000144277
WBInteraction000144282
WBInteraction000144288
WBInteraction000147218
WBInteraction000150146
WBInteraction000153187
WBInteraction000175501
WBInteraction000175509
WBInteraction000185261
WBInteraction000188291
WBInteraction000324317
WBInteraction000500989
WBInteraction000541211
WBInteraction000543506
WBInteraction000544354
WBInteraction000544420
WBInteraction000548551
WBInteraction000552361
WBInteraction000552710
WBInteraction000553432
WBInteraction000554977
WBInteraction000560525
WBInteraction000562232
WBInteraction000563557
WBInteraction000563655
WBInteraction000565291
WBInteraction000566920
WBInteraction000569336
WBInteraction000572227
WBInteraction000572682
WBInteraction000572935
WBInteraction000573358
WBInteraction000574525
WBInteraction000577486
WBInteraction000579715
WBInteraction000585995
WBInteraction000586334
WBProcessWBbiopr:00000134
Map_infoMapVPosition18.5005Error0.138896
PositivePositive_cloneY39B6AInferred_automaticallyFrom sequence, transcript, pseudogene data
Y39B6B
Mapping_dataMulti_point4527
5346
Pseudo_map_position
Reference (31)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene