WormBase Tree Display for Variation: WBVar00144830

WBVar00144830 Evidence: Paper_evidence: WBPaper00005353
    Person_evidence: WBPerson499
  Name: Public_name: e2432
    Other_name: F45E10.1d.1:c.1291_1456+159del
      F45E10.1c.1:c.1693_1858+159del
      F45E10.1g.1:c.1693_1858+159del
      F45E10.1e.1:c.433_598+159del
      F45E10.1b.1:c.1693_1858+159del
      F45E10.1a.1:c.1693_1858+159del
      F45E10.1h.1:c.1693_1858+159del
      F45E10.1f.1:c.769_934+159del
    HGVSg: CHROMOSOME_II:g.11067242_11067616del
  Sequence_details: SMap: S_parent: Sequence: F45E10
    Flanking_sequences: atccgacaaccaccaacgtacgatgttctt aaactttttcttttgataatttttgaatct
    Mapping_target: F45E10
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004572
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00006788
    Transcript: F45E10.1b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1b.1:c.1693_1858+159del
        cDNA_position: 1693-?
        CDS_position: 1693-?
        Protein_position: 565-?
        Intron_number: 12-13/22
        Exon_number: 12-13/23
      F45E10.1a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1a.1:c.1693_1858+159del
        cDNA_position: 1734-?
        CDS_position: 1693-?
        Protein_position: 565-?
        Intron_number: 13-14/23
        Exon_number: 13-14/24
      F45E10.1f.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1f.1:c.769_934+159del
        cDNA_position: 769-?
        CDS_position: 769-?
        Protein_position: 257-?
        Intron_number: 5-6/15
        Exon_number: 5-6/16
      F45E10.1c.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1c.1:c.1693_1858+159del
        cDNA_position: 1693-?
        CDS_position: 1693-?
        Protein_position: 565-?
        Intron_number: 12-13/23
        Exon_number: 12-13/24
      F45E10.1e.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1e.1:c.433_598+159del
        cDNA_position: 433-?
        CDS_position: 433-?
        Protein_position: 145-?
        Intron_number: 4-5/14
        Exon_number: 4-5/15
      F45E10.1d.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1d.1:c.1291_1456+159del
        cDNA_position: 1488-?
        CDS_position: 1291-?
        Protein_position: 431-?
        Intron_number: 10-11/20
        Exon_number: 10-11/21
      F45E10.1g.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1g.1:c.1693_1858+159del
        cDNA_position: 1693-?
        CDS_position: 1693-?
        Protein_position: 565-?
        Intron_number: 12-13/21
        Exon_number: 12-13/22
      F45E10.1h.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1h.1:c.1693_1858+159del
        cDNA_position: 1693-?
        CDS_position: 1693-?
        Protein_position: 565-?
        Intron_number: 12-13/21
        Exon_number: 12-13/22
  Genetics: Interpolated_map_position: II 3.16437
    Mapping_data: In_pos_neg_data: 4533
        4534
        4535
        4536
        4539
  Description: Phenotype: WBPhenotype:0000016 Paper_evidence: WBPaper00031872
        Curator_confirmed: WBPerson712
        Remark: % animals paralyzed after 60 min on 1mM aldicarb was significantly higher than % N2 animals paralyzed. Paper_evidence: WBPaper00031872
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003650 Paper_evidence: WBPaper00031872
              Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0007833 PATO:0001549 Paper_evidence: WBPaper00031872
                Curator_confirmed: WBPerson712
      WBPhenotype:0000195 Paper_evidence: WBPaper00051452
        Curator_confirmed: WBPerson7124
        EQ_annotations: Anatomy_term: WBbt:0006865 PATO:0000460 Paper_evidence: WBPaper00051452
                Curator_confirmed: WBPerson7124
      WBPhenotype:0000420 Paper_evidence: WBPaper00031872
        Curator_confirmed: WBPerson712
        Remark: % animals paralyzed after 60 min on 200mM levamisole was significantly higher than % N2 animals paralyzed under same conditions. Paper_evidence: WBPaper00031872
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00004019 Paper_evidence: WBPaper00031872
              Curator_confirmed: WBPerson712
  Reference: WBPaper00031872
    WBPaper00030276
    WBPaper00051452
  Method: Deletion_allele