WormBase Tree Display for Variation: WBVar00144542
expand all nodes | collapse all nodes | view schema
| WBVar00144542 | Name | Public_name | e2074 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | |||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00000255 | ||||||||
| WBStrain00023552 | |||||||||
| Laboratory | CB | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00003918 | |||||||
| Interactor | WBInteraction000556169 | ||||||||
| Genetics | Mapping_data | In_2_point | 2725 | ||||||
| In_multi_point | 1096 | ||||||||
| Description | Phenotype | WBPhenotype:0000052 | Paper_evidence | WBPaper00001032 | |||||
| Person_evidence | WBPerson261 | ||||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPerson712 | |||||||||
| Remark | maternal effect lethal mutation | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Penetrance | High | 96 percent Mel at 16C. 99 percent Mel at 25C | Paper_evidence | WBPaper00001032 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Temperature | 16C, 20C, 25C | Paper_evidence | WBPaper00001032 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000054 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Some animals are severely abnormal and die during larval development | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Penetrance | Incomplete | 68 percent of hatched animals die as larvae | Paper_evidence | WBPaper00001032 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000023 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000215 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Many newly hatched par-3 larvae also lack germ cell precursors | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Penetrance | Incomplete | 87 percent of surviving adult progeny lack germ cell precursors | Paper_evidence | WBPaper00001032 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000360 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | abnormal streaming | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Maternal | |||||||||
| WBPhenotype:0000395 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Some larvae develop into morphologically normal adults but lack mature gametes | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000748 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Equal first cleavage: AB and P1 blastomeres are nearly identical in size | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001105 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | In par-3 embryos, the posterior migration of the spindle complex does not occur | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001106 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | The orientation of the second cleavage in par-3 is highly variable. Sometimes both the anterior and posterior blastomeres divide longitudinally. Other times, embryos have a reversed wild-type pattern (anterior blastomere divides longitudinally and the posterior divides transversely); in others both blastomeres divide transversely | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Treatment | Staining with anti-tubulin antibody | Paper_evidence | WBPaper00001032 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001114 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | affects first two embryonic cell cycles | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Maternal | |||||||||
| WBPhenotype:0001120 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | In contrast to the wild-type division sequence, early blastomeres cleave synchronously during the first few cleavages | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001167 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | abnormal pseudocleavage | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Maternal | |||||||||
| WBPhenotype:0001302 | Paper_evidence | WBPaper00001032 | |||||||
| Person_evidence | WBPerson261 | ||||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPerson712 | |||||||||
| Remark | Embryos have either no or incomplete localization of P granules. Some par-3 embryos appear to localize P granules anteriorly as well as posteriorly. Many 4-cell stage par-3 embryos contain P granules in either the 2 middle or the 2 polar blastomeres | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Treatment | Staining with anti-P granule antibody | Paper_evidence | WBPaper00001032 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001504 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Penetrance | High | 91 percent of surviving adult progeny are agametic at 16C. 99 percent of surviving adult progeny are agametic at 25C | Paper_evidence | WBPaper00001032 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Temperature | 16C, 20C, 25C | Paper_evidence | WBPaper00001032 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001642 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | The orientation of the second embryonic cleavage is altered | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Treatment | Staining with anti-tubulin antibody | Paper_evidence | WBPaper00001032 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001681 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | 2nd cleavage spindle orientation variable, often both longitudinal (ectopic rotation in AB) | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Maternal | |||||||||
| Phenotype_not_observed | WBPhenotype:0000417 | Paper_evidence | WBPaper00001032 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001018 | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001032 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001032 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Reference | WBPaper00001032 | ||||||||
| WBPaper00026553 | |||||||||
| Method | Allele |
