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WormBase Tree Display for Variation: WBVar00143937

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Name Class

WBVar00143937EvidencePaper_evidenceWBPaper00001835
NamePublic_namee1350
Other_nameB0491.2.1:c.205C>T
B0491.2.2:c.205C>T
CE02104:p.Arg69Cys
HGVSgCHROMOSOME_II:g.11337498G>A
Sequence_detailsSMapS_parentSequenceB0491
Flanking_sequencestgtcatcggaagatctagcaagcgtgtccgtgtcaatatgaagagaccaacgctaccccaa
Mapping_targetB0491
Type_of_mutationSubstitutionctPaper_evidenceWBPaper00001835
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00004306
WBStrain00005655
WBStrain00006230
WBStrain00006236
WBStrain00006241
WBStrain00022554
LaboratoryCB
StatusLive
AffectsGeneWBGene00005016
TranscriptB0491.2.2 (12)
B0491.2.1 (12)
InteractorWBInteraction000052496
WBInteraction000052555
WBInteraction000052565
WBInteraction000052580
WBInteraction000537320
GeneticsInterpolated_map_positionII3.44049
Mapping_dataIn_2_point345
416
444
711
769
2596
2597
In_multi_point296
338
1054
1243
1385
2792
DescriptionPhenotypeWBPhenotype:0000070Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
RemarkTable 1Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
Phenotype_assayGenotypekaIs12 [col-19::gfp]Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
WBPhenotype:0000231Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Phenotype_assayTemperature20CPaper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Genotypehim-5(e1490)Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
WBPhenotype:0000502Paper_evidenceWBPaper00000906
Curator_confirmedWBPerson712
DominantPaper_evidenceWBPaper00000906
Curator_confirmedWBPerson712
WBPhenotype:0000505Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
RemarkHomozygous Ram.Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0006941PATO:0000460Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Life_stageWBls:0000056PATO:0000460Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Phenotype_assayTemperature20CPaper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Genotypehim-5(e1490)Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
WBPhenotype:0000583Paper_evidenceWBPaper00000906
WBPaper00005747
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPerson2987
RemarkLess dumpy at 25C than at 16C.Paper_evidenceWBPaper00000906
Curator_confirmedWBPerson712
Authors report "medium dpy" (Table 1)Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
RecessivePaper_evidenceWBPaper00000906
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000038PATO:0000460Person_evidenceWBPerson261
Curator_confirmedWBPerson712
WBls:0000041PATO:0000460Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Phenotype_assayGenotypekaIs12 [col-19::gfp]Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
Ease_of_scoringES3_Easy_to_scorePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000961Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
RemarkTable 1Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
Phenotype_assayGenotypekaIs12 [col-19::gfp]Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
WBPhenotype:0001412Paper_evidenceWBPaper00000465
WBPaper00005747
Curator_confirmedWBPerson712
WBPerson2987
RemarkAlae are beaded and loops are present.Paper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
Authors report "severe disruption with branching" (Table 1); "Furthermore, by comparison to the well-defined longitudinal ala ridges in the wild-type nematodes (Fig 1A,E), the alae of sqt-1(e1350) mutants appear to be composed of short, wispy fragments (Fig. 4C)."Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
Phenotype_assayTemperature25CPaper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
GenotypekaIs12 [col-19::gfp]Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
WBPhenotype:0001515Paper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
RemarkStruts are absent.Paper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
Phenotype_assayTemperature25CPaper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
WBPhenotype:0001517Paper_evidenceWBPaper00000465
WBPaper00005747
Curator_confirmedWBPerson712
WBPerson2987
RemarkAnnulae are severely effected; only smooth or rough surfaces are present.Paper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
Authors report "severe disruption" (Table 1)Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
Phenotype_assayTemperature25CPaper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
GenotypekaIs12 [col-19::gfp]Paper_evidenceWBPaper00005747
Curator_confirmedWBPerson2987
Phenotype_not_observedWBPhenotype:0000648Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
RemarkRay function was not severely disrupted by the morphological defects as most Ram males mated efficientlyPaper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000056PATO:0000460Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Phenotype_assayTemperature20CPaper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Genotypehim-5(e1490)Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
WBPhenotype:0000695Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0006748PATO:0000460Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Life_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Phenotype_assayTemperature20CPaper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
Genotypehim-5(e1490)Paper_evidenceWBPaper00001328
Curator_confirmedWBPerson712
WBPhenotype:0001516Paper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
Phenotype_assayTemperature25CPaper_evidenceWBPaper00000465
Curator_confirmedWBPerson712
WBPhenotype:0001687Paper_evidenceWBPaper00001280
Curator_confirmedWBPerson712
RemarkAnimals did not show any level of immunofluorescence significantly higher than wild-type controls.Paper_evidenceWBPaper00001280
Curator_confirmedWBPerson712
Reference (11)
MethodSubstitution_allele