WormBase Tree Display for Variation: WBVar00143414

WBVar00143414 Evidence: Paper_evidence: WBPaper00005913
    Accession_evidence: AJ505904
  Name: Public_name: e698
    Other_name (17)
    HGVSg: CHROMOSOME_I:g.11770152G>A
  Sequence_details: SMap: S_parent: Sequence: ZK1151
    Flanking_sequences: tctcgagagcattggcgagagaagttggtg aagcttcatgatcttctccttgatgagctt
    Mapping_target: ZK1151
    Type_of_mutation: Substitution: g a
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004199
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00006876
    Transcript (11)
    Interactor (16)
  Genetics: Interpolated_map_position: I 9.61491
    Mapping_data: In_2_point: 646
        647
      In_multi_point: 566
        567
  Description: Phenotype: WBPhenotype:0000030 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: generally poor growth Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: 50% Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0000071 Paper_evidence: WBPaper00040080
        Curator_confirmed: WBPerson712
      WBPhenotype:0000474 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: Mua (defective muscle attachment). Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: 50% Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0001099 Paper_evidence: WBPaper00038193
        Curator_confirmed: WBPerson351
        Remark: adults have a twisted nose Paper_evidence: WBPaper00038193
            Curator_confirmed: WBPerson351
      WBPhenotype:0001294 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: degenerate head, bent dorsally or ventrally; penetrance 50%; scoring easy to difficult (ES3/1). Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: 50% Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        Ease_of_scoring: ES3_Easy_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001297 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: adult male tail invariably thin fan and rays reduced in size Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: 50% Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0001652 Paper_evidence: WBPaper00046146
        Curator_confirmed: WBPerson12329
      WBPhenotype:0002534 Paper_evidence: WBPaper00031865
        Curator_confirmed: WBPerson712
        Remark: Animals exhibited significanlty less activation of lys-8, clec-85, dod-22, F55G11.7 and K08D8.5 and higher activation of abf-1 and abf-3 gene expression compared to wild-type animals as determined by qPCR. Paper_evidence: WBPaper00031865
            Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000505 Paper_evidence: WBPaper00001328
        Curator_confirmed: WBPerson712
        Remark: Males are not Ram. Paper_evidence: WBPaper00001328
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0006941 PATO:0000460 Paper_evidence: WBPaper00001328
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00001328
                Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20C Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
          Genotype: him-5(e1490) Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
      WBPhenotype:0001013 Paper_evidence: WBPaper00031865
        Curator_confirmed: WBPerson712
        Remark: Animals did not have altered susceptibility to P. aeruginosa at 15C or 25C. Paper_evidence: WBPaper00031865
            Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: Animals were exposed to P. aeruginosa starting at L4 stage. Paper_evidence: WBPaper00031865
              Curator_confirmed: WBPerson712
          Temperature: 25 Paper_evidence: WBPaper00031865
              Curator_confirmed: WBPerson712
  Reference: WBPaper00038193
    WBPaper00040080
    WBPaper00001328
    WBPaper00031865
    WBPaper00011329
    WBPaper00046146
  Method: Substitution_allele