Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Variation: WBVar00143314

expand all nodes | collapse all nodes | view schema

Name Class

WBVar00143314EvidencePaper_evidenceWBPaper00028438
NamePublic_namee580
Sequence_detailsMapping_targetK03E6
Type_of_mutationSubstitution
SeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00027058
LaboratoryCB
StatusLive
AffectsGeneWBGene00006741
InteractorWBInteraction000052184
GeneticsMapping_dataIn_2_point4453
DescriptionPhenotypeWBPhenotype:0001610Paper_evidenceWBPaper00028438
Curator_confirmedWBPerson2987
RemarkTable 1Paper_evidenceWBPaper00028438
Curator_confirmedWBPerson2987
Affected_byMoleculeWBMol:00007859Paper_evidenceWBPaper00028438
Curator_confirmedWBPerson2987
Phenotype_not_observedWBPhenotype:0000523Paper_evidenceWBPaper00028438
Curator_confirmedWBPerson2987
RemarkTable 1Paper_evidenceWBPaper00028438
Curator_confirmedWBPerson2987
Affected_byMoleculeWBMol:00001705Paper_evidenceWBPaper00028438
Curator_confirmedWBPerson2987
WBMol:00004563Paper_evidenceWBPaper00028438
Curator_confirmedWBPerson2987
WBPhenotype:0001612Paper_evidenceWBPaper00002358
Curator_confirmedWBPerson712
RemarkAnimals have a similar EC50 (1030 20 mM) compared to N2 (1050 25 mM).Paper_evidenceWBPaper00002358
Curator_confirmedWBPerson712
Phenotype_assayTreatment50 animals were scored for mobility for 10 sec. at each concentration of ethanol after 5 min exposure. EC50's (concentration at which 50% of the animals were immobile for >10 sec) were determined from a dose response curve over a minimum of 12 concentrations (mM). Immobility was used an as endpoint. Upon removal from ethanol, immobility was reversible within 10-15 min. Treatment and scoring of anesthetic responses are described in Sedensky and Meneely, 1987; Morgan et al. , 1990; Morgan and Sedensky, 1994.Paper_evidenceWBPaper00002358
Curator_confirmedWBPerson712
Temperature22-24CPaper_evidenceWBPaper00002358
Curator_confirmedWBPerson712
ReferenceWBPaper00015366
WBPaper00022645
WBPaper00015173
WBPaper00022026
WBPaper00002358
WBPaper00018537
WBPaper00028438
WBPaper00065317
MethodSubstitution_allele