WormBase Tree Display for Variation: WBVar00094620

WBVar00094620 Evidence: Paper_evidence: WBPaper00004137
  Name: Public_name: om84
    Other_name: F26A3.3.1:c.828_1034del
      CE27140:p.Leu276_Tyr345delinsPhe
    HGVSg: CHROMOSOME_I:g.7654980_7655231del
  Sequence_details: SMap: S_parent: Sequence: F26A3
    Flanking_sequences: gcactccgtcccacattatcgaagatattt taaccgttggacattcctaaataatcaaca
    Mapping_target: F26A3
    Type_of_mutation: Insertion
      Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00007150
      WBStrain00030624
    Laboratory: EL
    Status: Live
  Affects: Gene: WBGene00001214
    Transcript: F26A3.3.1 (11)
    Interactor: WBInteraction000502124
      WBInteraction000502125
  Genetics: Interpolated_map_position: I 2.21436
  Description: Phenotype: WBPhenotype:0000666 Paper_evidence: WBPaper00004137
        Curator_confirmed: WBPerson2021
        Remark: Small oocytes were slow to be ovulated Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00004137
          Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00004137
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000679 Paper_evidence: WBPaper00035228
        Curator_confirmed: WBPerson712
        Remark: PGL-1 staining in the germline differs from wild type; PGL-1 accumulates in large granules and dissociated from nuclei periphery. Paper_evidence: WBPaper00035228
            Curator_confirmed: WBPerson712
      WBPhenotype:0000812 Paper_evidence: WBPaper00004137
        Curator_confirmed: WBPerson2021
        Remark: Intersexual germ cells were only observed when the germ line switched from spermatogenesis to oogenesis Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00004137
          Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00004137
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: DAPI staining Paper_evidence: WBPaper00004137
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001260 Paper_evidence: WBPaper00004137
        Curator_confirmed: WBPerson2021
        Remark: Mutants typically produced small oocytes with unusual chromosome morphology Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00004137
          Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00004137
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: DAPI staining Paper_evidence: WBPaper00004137
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001694 Paper_evidence: WBPaper00004137
        Curator_confirmed: WBPerson2021
        Remark: The spermatogenesis-to-oogenesis switch occurred several hours later in ego-1 mutants than in controls Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00004137
          Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00004137
                Curator_confirmed: WBPerson2021
      WBPhenotype:0001945 Paper_evidence: WBPaper00004137
        Curator_confirmed: WBPerson557
        Remark: Small oocytes were slow to be ovulated Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson557
        Recessive: Paper_evidence: WBPaper00004137
          Curator_confirmed: WBPerson557
        Variation_effect: Null: Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson557
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00004137
                Curator_confirmed: WBPerson557
    Phenotype_not_observed: WBPhenotype:0001759 Paper_evidence: WBPaper00031962
        Curator_confirmed: WBPerson712
        Remark: These proteins are not required for piRNA expression, as determined by comparable levels of 21U-RNA on Northern blot and or qRT-PCR to that of wild-type. Paper_evidence: WBPaper00031962
            Curator_confirmed: WBPerson712
        EQ_annotations: GO_term: GO:0034585 PATO:0000460 Paper_evidence: WBPaper00031962
                Curator_confirmed: WBPerson712
  Reference: WBPaper00035228
    WBPaper00004137
    WBPaper00031962
    WBPaper00023654
    WBPaper00011141
    WBPaper00015554
  Method: Deletion_and_insertion_allele