WormBase Tree Display for Variation: WBVar00093838

WBVar00093838 Name: Public_name: ok2736
    Other_name (16)
    HGVSg: CHROMOSOME_II:g.11059366_11059666del
  Sequence_details: SMap: S_parent: Sequence: F45E10
    Flanking_sequences: tgcggcaccgtgcatgaacattcggattgt gagttgcagccagaggatcgtttcgaagat
    Mapping_target: F45E10
    Type_of_mutation: Deletion
    PCR_product: ok2736_external
      ok2736_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00032757
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00006788
    Transcript: F45E10.1b.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1b.1:c.3363_3663del
        HGVSp: CE31347:p.Ile1122GlnfsTer14
        cDNA_position: 3363-3663
        CDS_position: 3363-3663
        Protein_position: 1121-1221
        Exon_number: 21/23
        Codon_change: tcAATCAAGGTTACTGTAAACGTGGACATCGCTGGAGAAATCAGTTCGATCGTTAACCCGGACAAAGAGATAATCGTAGGATATCTTGCCATGCCAACCAGTCAGTCATGCTGGAAAGACATTGATGTTTCTATTCTAGGACTATTTGAAGTCTACCTATCCAGAATTGATGTGGAGCATCAACTTGGAATCGATGCTCGTGATTCTATCCTTGGCTATCAAATTGGTGAACTTCGACGCGTCATTGGAGACTCCACAACCATGATAACCAGCCATCCAACTGACATTCTTACTTCCTCAACT/tc
        Amino_acid_change: SIKVTVNVDIAGEISSIVNPDKEIIVGYLAMPTSQSCWKDIDVSILGLFEVYLSRIDVEHQLGIDARDSILGYQIGELRRVIGDSTTMITSHPTDILTSST/X
      F45E10.1a.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1a.1:c.3465_3765del
        HGVSp: CE31346:p.Ile1156GlnfsTer14
        cDNA_position: 3506-3806
        CDS_position: 3465-3765
        Protein_position: 1155-1255
        Exon_number: 22/24
        Codon_change: tcAATCAAGGTTACTGTAAACGTGGACATCGCTGGAGAAATCAGTTCGATCGTTAACCCGGACAAAGAGATAATCGTAGGATATCTTGCCATGCCAACCAGTCAGTCATGCTGGAAAGACATTGATGTTTCTATTCTAGGACTATTTGAAGTCTACCTATCCAGAATTGATGTGGAGCATCAACTTGGAATCGATGCTCGTGATTCTATCCTTGGCTATCAAATTGGTGAACTTCGACGCGTCATTGGAGACTCCACAACCATGATAACCAGCCATCCAACTGACATTCTTACTTCCTCAACT/tc
        Amino_acid_change: SIKVTVNVDIAGEISSIVNPDKEIIVGYLAMPTSQSCWKDIDVSILGLFEVYLSRIDVEHQLGIDARDSILGYQIGELRRVIGDSTTMITSHPTDILTSST/X
      F45E10.1f.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1f.1:c.2754_3054del
        HGVSp: CE43986:p.Ile919GlnfsTer14
        cDNA_position: 2754-3054
        CDS_position: 2754-3054
        Protein_position: 918-1018
        Exon_number: 15/16
        Codon_change: tcAATCAAGGTTACTGTAAACGTGGACATCGCTGGAGAAATCAGTTCGATCGTTAACCCGGACAAAGAGATAATCGTAGGATATCTTGCCATGCCAACCAGTCAGTCATGCTGGAAAGACATTGATGTTTCTATTCTAGGACTATTTGAAGTCTACCTATCCAGAATTGATGTGGAGCATCAACTTGGAATCGATGCTCGTGATTCTATCCTTGGCTATCAAATTGGTGAACTTCGACGCGTCATTGGAGACTCCACAACCATGATAACCAGCCATCCAACTGACATTCTTACTTCCTCAACT/tc
        Amino_acid_change: SIKVTVNVDIAGEISSIVNPDKEIIVGYLAMPTSQSCWKDIDVSILGLFEVYLSRIDVEHQLGIDARDSILGYQIGELRRVIGDSTTMITSHPTDILTSST/X
      F45E10.1c.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1c.1:c.3678_3978del
        HGVSp: CE33783:p.Ile1227GlnfsTer14
        cDNA_position: 3678-3978
        CDS_position: 3678-3978
        Protein_position: 1226-1326
        Exon_number: 22/24
        Codon_change: tcAATCAAGGTTACTGTAAACGTGGACATCGCTGGAGAAATCAGTTCGATCGTTAACCCGGACAAAGAGATAATCGTAGGATATCTTGCCATGCCAACCAGTCAGTCATGCTGGAAAGACATTGATGTTTCTATTCTAGGACTATTTGAAGTCTACCTATCCAGAATTGATGTGGAGCATCAACTTGGAATCGATGCTCGTGATTCTATCCTTGGCTATCAAATTGGTGAACTTCGACGCGTCATTGGAGACTCCACAACCATGATAACCAGCCATCCAACTGACATTCTTACTTCCTCAACT/tc
        Amino_acid_change: SIKVTVNVDIAGEISSIVNPDKEIIVGYLAMPTSQSCWKDIDVSILGLFEVYLSRIDVEHQLGIDARDSILGYQIGELRRVIGDSTTMITSHPTDILTSST/X
      F45E10.1e.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1e.1:c.2418_2718del
        HGVSp: CE34020:p.Ile807GlnfsTer14
        cDNA_position: 2418-2718
        CDS_position: 2418-2718
        Protein_position: 806-906
        Exon_number: 14/15
        Codon_change: tcAATCAAGGTTACTGTAAACGTGGACATCGCTGGAGAAATCAGTTCGATCGTTAACCCGGACAAAGAGATAATCGTAGGATATCTTGCCATGCCAACCAGTCAGTCATGCTGGAAAGACATTGATGTTTCTATTCTAGGACTATTTGAAGTCTACCTATCCAGAATTGATGTGGAGCATCAACTTGGAATCGATGCTCGTGATTCTATCCTTGGCTATCAAATTGGTGAACTTCGACGCGTCATTGGAGACTCCACAACCATGATAACCAGCCATCCAACTGACATTCTTACTTCCTCAACT/tc
        Amino_acid_change: SIKVTVNVDIAGEISSIVNPDKEIIVGYLAMPTSQSCWKDIDVSILGLFEVYLSRIDVEHQLGIDARDSILGYQIGELRRVIGDSTTMITSHPTDILTSST/X
      F45E10.1d.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1d.1:c.3276_3576del
        HGVSp: CE34019:p.Ile1093GlnfsTer14
        cDNA_position: 3473-3773
        CDS_position: 3276-3576
        Protein_position: 1092-1192
        Exon_number: 20/21
        Codon_change: tcAATCAAGGTTACTGTAAACGTGGACATCGCTGGAGAAATCAGTTCGATCGTTAACCCGGACAAAGAGATAATCGTAGGATATCTTGCCATGCCAACCAGTCAGTCATGCTGGAAAGACATTGATGTTTCTATTCTAGGACTATTTGAAGTCTACCTATCCAGAATTGATGTGGAGCATCAACTTGGAATCGATGCTCGTGATTCTATCCTTGGCTATCAAATTGGTGAACTTCGACGCGTCATTGGAGACTCCACAACCATGATAACCAGCCATCCAACTGACATTCTTACTTCCTCAACT/tc
        Amino_acid_change: SIKVTVNVDIAGEISSIVNPDKEIIVGYLAMPTSQSCWKDIDVSILGLFEVYLSRIDVEHQLGIDARDSILGYQIGELRRVIGDSTTMITSHPTDILTSST/X
      F45E10.1g.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1g.1:c.3555_3855del
        HGVSp: CE44133:p.Ile1186GlnfsTer14
        cDNA_position: 3555-3855
        CDS_position: 3555-3855
        Protein_position: 1185-1285
        Exon_number: 21/22
        Codon_change: tcAATCAAGGTTACTGTAAACGTGGACATCGCTGGAGAAATCAGTTCGATCGTTAACCCGGACAAAGAGATAATCGTAGGATATCTTGCCATGCCAACCAGTCAGTCATGCTGGAAAGACATTGATGTTTCTATTCTAGGACTATTTGAAGTCTACCTATCCAGAATTGATGTGGAGCATCAACTTGGAATCGATGCTCGTGATTCTATCCTTGGCTATCAAATTGGTGAACTTCGACGCGTCATTGGAGACTCCACAACCATGATAACCAGCCATCCAACTGACATTCTTACTTCCTCAACT/tc
        Amino_acid_change: SIKVTVNVDIAGEISSIVNPDKEIIVGYLAMPTSQSCWKDIDVSILGLFEVYLSRIDVEHQLGIDARDSILGYQIGELRRVIGDSTTMITSHPTDILTSST/X
      F45E10.1h.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: F45E10.1h.1:c.3342_3642del
        HGVSp: CE44088:p.Ile1115GlnfsTer14
        cDNA_position: 3342-3642
        CDS_position: 3342-3642
        Protein_position: 1114-1214
        Exon_number: 20/22
        Codon_change: tcAATCAAGGTTACTGTAAACGTGGACATCGCTGGAGAAATCAGTTCGATCGTTAACCCGGACAAAGAGATAATCGTAGGATATCTTGCCATGCCAACCAGTCAGTCATGCTGGAAAGACATTGATGTTTCTATTCTAGGACTATTTGAAGTCTACCTATCCAGAATTGATGTGGAGCATCAACTTGGAATCGATGCTCGTGATTCTATCCTTGGCTATCAAATTGGTGAACTTCGACGCGTCATTGGAGACTCCACAACCATGATAACCAGCCATCCAACTGACATTCTTACTTCCTCAACT/tc
        Amino_acid_change: SIKVTVNVDIAGEISSIVNPDKEIIVGYLAMPTSQSCWKDIDVSILGLFEVYLSRIDVEHQLGIDARDSILGYQIGELRRVIGDSTTMITSHPTDILTSST/X
  Isolation: Mutagen: EMS
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele