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WormBase Tree Display for Variation: WBVar00090682

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Name Class

WBVar00090682NamePublic_namen3314
Sequence_detailsSeqStatusNot_sequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00027366
WBStrain00027389
LaboratoryMT
StatusLive
AffectsGeneWBGene00003387
DescriptionPhenotype (10)
Phenotype_not_observedWBPhenotype:0000643Paper_evidenceWBPaper00036766
Curator_confirmedWBPerson712
RemarkMutants grown on NGM plates exhibited superficially normal locomotion.Paper_evidenceWBPaper00036766
Curator_confirmedWBPerson712
WBPhenotype:0001462Paper_evidenceWBPaper00032335
Curator_confirmedWBPerson712
RemarkAnimals exhibited wild-type chemotaxis to NaCl.Paper_evidenceWBPaper00032335
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00003571Paper_evidenceWBPaper00032335
Curator_confirmedWBPerson712
Phenotype_assayTreatmentAnimals were tested for response to 25 mM NaCl.Paper_evidenceWBPaper00032335
Curator_confirmedWBPerson712
WBPhenotype:0001811Paper_evidenceWBPaper00031915
Curator_confirmedWBPerson2021
Remarkmod-5(n3314) mutants were further susceptible to the fat-reducing effects of exogenously administered serotoninPaper_evidenceWBPaper00031915
Curator_confirmedWBPerson2021
Phenotype_assayTreatmentReduced fat content of 5-HT-treated animals was visualized by Nile red staining and confirmed by thin-layer chromatography (TLC) quantitation of total triglycerides extracted from vehicle- and 5-HT-treated worms and by Sudan black fat stainingPaper_evidenceWBPaper00031915
Curator_confirmedWBPerson2021
Disease_infoModels_diseaseDOID:809
Models_disease_in_annotationWBDOannot00000682
Reference (18)
MethodAllele