WormBase Tree Display for Variation: WBVar00089204

WBVar00089204 Evidence: Paper_evidence: WBPaper00003383
  Name: Public_name: mu39
    Other_name: W08D2.1.1:c.497G>A
      W08D2.1.2:c.497G>A
      W08D2.1.3:c.497G>A
      CE25152:p.Cys166Tyr
    HGVSg: CHROMOSOME_IV:g.9814467C>T
  Sequence_details: SMap: S_parent: Sequence: W08D2
    Flanking_sequences: aaggctgtaatactggaaatctaacagaat tggatgtgacagtaaaccaggaatgcagag
    Mapping_target: W08D2
    Type_of_mutation: Substitution: g a
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004817
    Laboratory: CF
    Status: Live
  Affects: Gene: WBGene00001188
    Transcript: W08D2.1.3 (12)
      W08D2.1.1 (12)
      W08D2.1.2 (12)
    Interactor: WBInteraction000538541
      WBInteraction000538545
      WBInteraction000538550
      WBInteraction000538553
  Genetics: Interpolated_map_position: IV 4.42291
  Description: Phenotype (16)
    Phenotype_not_observed: WBPhenotype:0000195 Paper_evidence: WBPaper00005809
        Curator_confirmed: WBPerson2987
        Remark: Table 3 Paper_evidence: WBPaper00005809
            Curator_confirmed: WBPerson2987
          "In contrast to the results with an unc-5 hypomorphic allele, the frequency of DTC migration defects of an unc-5 null allele was not significantly increased by any of the mutations in genes encoding growth factor-like molecules that we examined (Table 3)." Paper_evidence: WBPaper00005809
            Curator_confirmed: WBPerson2987
        EQ_annotations: Anatomy_term: WBbt:0006865 PATO:0000460 Paper_evidence: WBPaper00005809
                Curator_confirmed: WBPerson2987
          GO_term: GO:0016477 PATO:0000460 Paper_evidence: WBPaper00005809
                Curator_confirmed: WBPerson2987
        Phenotype_assay: Genotype: unc-5(e152) Paper_evidence: WBPaper00005809
              Curator_confirmed: WBPerson2987
            unc-5(e53) Paper_evidence: WBPaper00005809
              Curator_confirmed: WBPerson2987
      WBPhenotype:0000296 Paper_evidence: WBPaper00002582
        Curator_confirmed: WBPerson712
        Remark: Animals do not exhibit crumpled spicules; crumpled spicules is characteristic of other egl-20 mutants. Paper_evidence: WBPaper00002582
            Curator_confirmed: WBPerson712
      WBPhenotype:0000298 Paper_evidence: WBPaper00002582
        Curator_confirmed: WBPerson712
        Remark: Animals do not exhibit incomplete migration of rays 1 and 2 into the tail; incomplete migration of these rays is characteristic of other egl-20 mutants. Paper_evidence: WBPaper00002582
            Curator_confirmed: WBPerson712
      WBPhenotype:0000827 Paper_evidence: WBPaper00002582
        Curator_confirmed: WBPerson712
        Remark: Animals do not exhibit A/P reversal of the V5 lineage; this A/P reversal is characteristic of other egl-20 mutants. Paper_evidence: WBPaper00002582
            Curator_confirmed: WBPerson712
      WBPhenotype:0001235 Paper_evidence: WBPaper00004436
        Curator_confirmed: WBPerson2987
        Remark: At all temperatures tested, egl-20(mu39) animals exhibited wild type V5 cell division polarity (Table 1) Paper_evidence: WBPaper00004436
            Curator_confirmed: WBPerson2987
        EQ_annotations: Anatomy_term: WBbt:0004890 PATO:0000460 Paper_evidence: WBPaper00004436
                Curator_confirmed: WBPerson2987
            WBbt:0004876 PATO:0000460 Paper_evidence: WBPaper00004436
                Curator_confirmed: WBPerson2987
            WBbt:0004250 PATO:0000460 Paper_evidence: WBPaper00004436
                Curator_confirmed: WBPerson2987
            WBbt:0007446 PATO:0000460 Paper_evidence: WBPaper00004436
                Curator_confirmed: WBPerson2987
            WBbt:0004246 PATO:0000460 Paper_evidence: WBPaper00004436
                Curator_confirmed: WBPerson2987
            WBbt:0007463 PATO:0000460 Paper_evidence: WBPaper00004436
                Curator_confirmed: WBPerson2987
          Life_stage: WBls:0000024 PATO:0000460 Paper_evidence: WBPaper00004436
                Curator_confirmed: WBPerson2987
      WBPhenotype:0001278 Paper_evidence: WBPaper00057074
        Curator_confirmed: WBPerson712
        Remark: neurons did not show a loss in unc-25::GFP expression Paper_evidence: WBPaper00057074
            Curator_confirmed: WBPerson712
        Image: WBPicture0000014913 Paper_evidence: WBPaper00057074
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0005027 PATO:0000460 Paper_evidence: WBPaper00057074
                Curator_confirmed: WBPerson712
            WBbt:0005021 PATO:0000460 Paper_evidence: WBPaper00057074
                Curator_confirmed: WBPerson712
  Reference: WBPaper00043908
    WBPaper00004436
    WBPaper00025979
    WBPaper00005809
    WBPaper00002582
    WBPaper00057074
  Method: Substitution_allele