WormBase Tree Display for Variation: WBVar00089199

WBVar00089199 Evidence: Paper_evidence: WBPaper00001767
  Name: Public_name: mu26
    Other_name: C07H6.7.2:c.635G>A
      CE03975:p.Trp212Ter
      C07H6.7.1:c.635G>A
    HGVSg: CHROMOSOME_III:g.7529776C>T
  Sequence_details: SMap: S_parent: Sequence: C07H6
    Flanking_sequences: atataaaacactctgtttcaggtcaaaattt gtttcaaaatcgacgaatgaagcacaaaaaa
    Mapping_target: C07H6
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00001767
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: CF
    Status: Live
  Affects: Gene: WBGene00003024
    Transcript: C07H6.7.2 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: C07H6.7.2:c.635G>A
        HGVSp: CE03975:p.Trp212Ter
        cDNA_position: 740
        CDS_position: 635
        Protein_position: 212
        Exon_number: 5/7
        Codon_change: tGg/tAg
        Amino_acid_change: W/*
      C07H6.7.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: C07H6.7.1:c.635G>A
        HGVSp: CE03975:p.Trp212Ter
        cDNA_position: 678
        CDS_position: 635
        Protein_position: 212
        Exon_number: 5/7
        Codon_change: tGg/tAg
        Amino_acid_change: W/*
  Genetics: Interpolated_map_position: III -0.681234
  Description: Phenotype: WBPhenotype:0000227 Paper_evidence: WBPaper00001861
        Curator_confirmed: WBPerson712
        Remark: Male turning ability similar to CP neuron ablation; many missed and some sloppy. Paper_evidence: WBPaper00001861
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00001861
              Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00001861
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00001861
                Curator_confirmed: WBPerson712
      WBPhenotype:0000424 Paper_evidence: WBPaper00001861
        Curator_confirmed: WBPerson712
        Remark: Somata and processes of the ventral nerve cord are not serotonin-IR (immunoreactive), although the serotonin-IR neurons in the head and tail were normal. Paper_evidence: WBPaper00001861
            Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00001861
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0005300 PATO:0000460 Paper_evidence: WBPaper00001861
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00001861
                Curator_confirmed: WBPerson712
  Reference: WBPaper00001861
  Method: Substitution_allele