Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Variation: WBVar00088809

expand all nodes | collapse all nodes | view schema

Name Class

WBVar00088809NamePublic_namemd176
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00026411
WBStrain00027329
LaboratoryRM
StatusLive
AffectsGeneWBGene00001179
InteractorWBInteraction000524571
WBInteraction000524572
WBInteraction000524575
DescriptionPhenotype (26)
Phenotype_not_observedWBPhenotype:0000017Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
RemarkFraction of animals moving after exposure to 0.5mM aldicarb is ~0.026 compared to N2 ~0.03.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00003650Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
WBPhenotype:0000315Paper_evidenceWBPaper00037778
Curator_confirmedWBPerson2987
Remarkegl-10(md176) mutants exhibited a wild type avoidance response to anterior body touch (Figure 1c)Paper_evidenceWBPaper00037778
Curator_confirmedWBPerson2987
WBPhenotype:0001618Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
RemarkAnimals exhibit an EC50 for halothane statistically insignificant from that of N2 as determined by a concentration-response curve based on animal dispersal indexes.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Variation_effectHypomorph_reduction_of_functionPaper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00001705Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
WBPhenotype:0001619Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
RemarkAnimals exhibit an EC50 for isoflurane statistically insignificant from that of N2 as determined by a concentration-response curve based on animal dispersal indexes.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Variation_effectHypomorph_reduction_of_functionPaper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00004563Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
WBPhenotype:0002077Paper_evidenceWBPaper00041132
Curator_confirmedWBPerson557
Remarkegl-10(md176) mutants are hypersensitive to the effects of exogenous dopamine on locomotion rate.Paper_evidenceWBPaper00041132
Curator_confirmedWBPerson557
WBPhenotype:0002199Paper_evidenceWBPaper00037778
Curator_confirmedWBPerson2987
RemarkThe egl-10(md176) mutation did not affect the calcium transients in ASH neurons in response to high osmolarity (1M glycerol) (Figure 4a), 10 millimolar quinine (Figure 4b), or 1 millimolar copper (Figure 4c)Paper_evidenceWBPaper00037778
Curator_confirmedWBPerson2987
ReferenceWBPaper00043908
WBPaper00035198
WBPaper00015719
WBPaper00004721
WBPaper00035489
WBPaper00037778
WBPaper00041132
WBPaper00065340
MethodAllele