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WormBase Tree Display for Variation: WBVar00088108

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Name Class

WBVar00088108EvidencePaper_evidenceWBPaper00003101
NamePublic_namejs21
Other_nameF56A8.7b.1:c.722C>T
CE16127:p.Ala241Val
F56A8.7a.2:c.722C>T
F56A8.7a.1:c.722C>T
CE28035:p.Ala241Val
HGVSgCHROMOSOME_III:g.13280587C>T
Sequence_detailsSMapS_parentSequenceF56A8
Flanking_sequencesttgatcgaattgagtacaatgtggagcacggaaagaatttgttgatcgagcagtagctga
Mapping_targetF56A8
Type_of_mutationSubstitutionctPaper_evidenceWBPaper00003101
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00029044
LaboratoryNM
StatusLive
AffectsGeneWBGene00006798
TranscriptF56A8.7b.1 (12)
F56A8.7a.2 (12)
F56A8.7a.1 (12)
GeneticsInterpolated_map_positionIII21.1995
DescriptionPhenotypeWBPhenotype:0000017Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
RemarkMeasured by the fraction of animals moving after incubation on 0.5mM aldicarb agar pads.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00003650Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
WBPhenotype:0000641Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
RemarkDispersal index in the absence of anesthetic ~0.64 was significantly reduced compared to N2 ~0.90.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Phenotype_assayTreatmentDispersal assay as reported in Crowder et al.1996; van Swinderen et al. 1997.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
WBPhenotype:0001482Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Remark~4.8 body bends/minute compared with N2, ~18.6 BBM.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
WBPhenotype:0001609Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
RemarkEC50 ~0.13 compared with N2 EC50 ~0.75 vol%.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00004563Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
WBPhenotype:0001611Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
RemarkEC50 ~0.17 compared with N2 EC50 ~0.42 vol%.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00001705Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000680Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
RemarkMeasured by the fraction of animals moving after incubation on 0.1mM aldicarb agar pads.Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00003650Paper_evidenceWBPaper00004721
Curator_confirmedWBPerson712
ReferenceWBPaper00004721
WBPaper00018539
MethodSubstitution_allele