WormBase Tree Display for Variation: WBVar00088012

WBVar00088012 Evidence: Paper_evidence: WBPaper00001032
  Name: Public_name: it32
    Other_name (29)
    HGVSg: CHROMOSOME_V:g.14120146G>A
  Sequence_details: SMap: S_parent: Sequence: H39E23
    Flanking_sequences: ggtgtcggaccacaaacctctccagctgtt aagtaccaacagaagatgcaacttcatcat
    Mapping_target: H39E23
    Type_of_mutation: Substitution: c t
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: KK
    Status: Live
  Affects: Gene: WBGene00003916
    Transcript (17)
    Interactor: WBInteraction000503736
  Genetics: Interpolated_map_position: V 6.15304
  Description: Phenotype: WBPhenotype:0000052 Paper_evidence: WBPaper00001032
        Curator_confirmed: WBPerson2021
        Penetrance: Complete: 100 percent Paper_evidence: WBPaper00001032
              Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001032
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00001032
                Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00001032
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 16C, 20C, 25C Paper_evidence: WBPaper00001032
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001637 Paper_evidence: WBPaper00001032
        Curator_confirmed: WBPerson2021
        Remark: Almost no terminal stage par-1 embryos produce any intestinal cells Paper_evidence: WBPaper00001032
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001032
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00001032
                Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00001032
            Curator_confirmed: WBPerson2021
      WBPhenotype:0001642 Paper_evidence: WBPaper00001032
        Curator_confirmed: WBPerson2021
        Remark: Embryos exhibit altered early cleavage patterns Paper_evidence: WBPaper00001032
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001032
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00001032
                Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00001032
            Curator_confirmed: WBPerson2021
      WBPhenotype:0001794 Paper_evidence: WBPaper00032091
        Curator_confirmed: WBPerson2021
        Remark: LSM-1 granules formed in both somatic and germline blastomeres unlike wild-type Paper_evidence: WBPaper00032091
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00032091
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: anti-GFP staining Paper_evidence: WBPaper00032091
              Curator_confirmed: WBPerson2021
          Genotype: axIs1437 [pie-1p::LAP:LSM-1] Paper_evidence: WBPaper00032091
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001826 Paper_evidence: WBPaper00032091
        Curator_confirmed: WBPerson2021
        Remark: In par-1 mutant embryos, nos-2 RNA was degraded throughout the embryo. This is in contrast to wild-type embryos, where nos-2 is degraded in somatic blastomeres, and is maintained only in germline blastomeres Paper_evidence: WBPaper00032091
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00032091
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: In situ hybridization of nos-2 mRNA Paper_evidence: WBPaper00032091
              Curator_confirmed: WBPerson2021
          Genotype: axIs1437 [pie-1p::LAP:LSM-1] Paper_evidence: WBPaper00032091
              Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000417 Paper_evidence: WBPaper00001032
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001032
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00001032
                Curator_confirmed: WBPerson2021
      WBPhenotype:0001018 Paper_evidence: WBPaper00001032
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001032
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00001032
                Curator_confirmed: WBPerson2021
  Reference: WBPaper00001032
    WBPaper00032091
  Method: Substitution_allele