WormBase Tree Display for Variation: WBVar00000371

WBVar00000371 Evidence: Paper_evidence: WBPaper00002243
  Name: Public_name: b245
    Other_name: CE02878:p.Gly339Arg
      T19C3.8.1:c.1015G>A
    HGVSg: CHROMOSOME_III:g.633043C>T
  Sequence_details: SMap: S_parent: Sequence: T19C3
    Flanking_sequences: aacggagttctaaatctcacccgagcactc gagatgttcctggacggccgatgatctcta
    Mapping_target: T19C3
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00002243
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00005816
    Laboratory: DH
    Status: Live
  Linked_to: WBVar00000372
    WBVar00000373
    WBVar00000374
    WBVar00000375
  Affects: Gene: WBGene00001412
    Transcript: T19C3.8.1 (12)
    Interactor: WBInteraction000501744
      WBInteraction000502809
      WBInteraction000521254
      WBInteraction000534749
      WBInteraction000557073
      WBInteraction000557076
      WBInteraction000558238
      WBInteraction000576793
  Genetics: Interpolated_map_position: III -26.4551
    Mapping_data: In_2_point: 1607
        1608
      In_multi_point: 856
        857
  Description: Phenotype: WBPhenotype:0000050 Paper_evidence: WBPaper00035459
        Curator_confirmed: WBPerson2021
        Remark: At 20C, fem-2(b245) mutants led to only modest embryonic lethality Paper_evidence: WBPaper00035459
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000105 Paper_evidence: WBPaper00028730
        Curator_confirmed: WBPerson712
        Remark: animals exhibit oocyte maturation defects; however, after being crossedwith wild-type (N2) males, fem-2 (b245ts) mutant females were able to produce progeny, Paper_evidence: WBPaper00028730
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00028730
              Curator_confirmed: WBPerson712
      WBPhenotype:0000290 Paper_evidence: WBPaper00028730
        Curator_confirmed: WBPerson712
        Remark: RT-PCR quantification of the sperm-specific marker msp-77 clearly showed that sperm were in fact absent Paper_evidence: WBPaper00028730
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00028730
              Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0001779 Paper_evidence: WBPaper00035664
        Curator_confirmed: WBPerson2021
        Remark: Expression of miRNAs 35-41 is unaffected Paper_evidence: WBPaper00035664
            Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00035664
              Curator_confirmed: WBPerson2021
  Reference (17)
  Method: Substitution_allele