WormBase Tree Display for Variation: WBVar00000258

WBVar00000258 Evidence: Paper_evidence: WBPaper00029172
  Name: Public_name: ar492
    Other_name (16)
    HGVSg: CHROMOSOME_IV:g.3117807A>C
  Sequence_details: SMap: S_parent: Sequence: Y67D8C
    Flanking_sequences: taatacattcgtcatgatgaccctcttcaa gagatcaacgctcgtaagattcacggagaa
    Mapping_target: Y67D8C
    Type_of_mutation: Substitution: t g Paper_evidence: WBPaper00029172
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00008044
    Laboratory: GS
    Status: Live
  Affects: Gene: WBGene00305860
      WBGene00305861
      WBGene00003153
      WBGene00305862
    Transcript (14)
    Interactor: WBInteraction000502834
      WBInteraction000502835
  Genetics: Interpolated_map_position: IV -5.83477
  Description: Phenotype: WBPhenotype:0000315 Paper_evidence: WBPaper00046308
        Curator_confirmed: WBPerson10425
      WBPhenotype:0000643 Paper_evidence: WBPaper00004883
        Curator_confirmed: WBPerson712
        Remark: Animals moved very slowly and had a tendency to curl. Paper_evidence: WBPaper00004883
            Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: dpy-20(e1282); arIs37[pmyo-3::ssGFP] Paper_evidence: WBPaper00004883
              Curator_confirmed: WBPerson712
      WBPhenotype:0000644 Paper_evidence: WBPaper00029172
        Curator_confirmed: WBPerson557
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00029172
            Curator_confirmed: WBPerson557
      WBPhenotype:0001426 Paper_evidence: WBPaper00004883
          WBPaper00029172
        Curator_confirmed: WBPerson712
          WBPerson557
        Remark: Animals exhibited an accumulation of GFP in the pseudocoelom, rather than being taken up and degraded by coelomocytes as occurred in control animals. Paper_evidence: WBPaper00004883
            Curator_confirmed: WBPerson712
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00029172
            Curator_confirmed: WBPerson557
        Phenotype_assay: Genotype: dpy-20(e1282); arIs37[pmyo-3::ssGFP] Paper_evidence: WBPaper00004883
              Curator_confirmed: WBPerson712
      WBPhenotype:0001762 Paper_evidence: WBPaper00004883
        Curator_confirmed: WBPerson712
        Remark: Oocytes did not take up as much yolk as observed for oocytes in control animals, rather yolk granules accumulated in the pseudocoelom. Paper_evidence: WBPaper00004883
            Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: dpy-20(e1282); arIs37[pmyo-3::ssGFP] Paper_evidence: WBPaper00004883
              Curator_confirmed: WBPerson712
  Reference: WBPaper00004883
    WBPaper00029172
    WBPaper00046308
    WBPaper00061172
  Remark: Variation stub/paper connection generated from the May 2021 NN VFP dataset.
    Created by WBPerson51134 from the NN_VFP_triage_pipeline
  Method: Substitution_allele