WormBase Tree Display for Variation: WBVar00000034
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| WBVar00000034 | Name | Public_name | ad572 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | |||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00005482 | ||||||||
| Laboratory | DA | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00001135 | |||||||
| Genetics | Mapping_data | In_2_point | 6196 | ||||||
| In_multi_point | 1835 | ||||||||
| 1836 | |||||||||
| 1863 | |||||||||
| 2462 | |||||||||
| 2463 | |||||||||
| In_pos_neg_data | 7089 | ||||||||
| 7090 | |||||||||
| 7091 | |||||||||
| Description | Phenotype | WBPhenotype:0000011 | Paper_evidence | WBPaper00036766 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Mutants of eat-4 were more resistant to fluoxetine-induced paralysis compared to WT animals. | Paper_evidence | WBPaper00036766 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Single mutants exhibited similar resistance to fluoxetine to ser-7. | Paper_evidence | WBPaper00036766 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Affected_by | Molecule | WBMol:00005058 | Paper_evidence | WBPaper00036766 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000330 | Paper_evidence | WBPaper00001709 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | weak relaxation defect | Paper_evidence | WBPaper00001709 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Null | Paper_evidence | WBPaper00001709 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0003681 | PATO:0000460 | Paper_evidence | WBPaper00001709 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00001709 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000634 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Normal pumps are interspersed with abnormal pumps in which corpus contractions are feeble but long-lasting, and terminal bulb contractions are long-lasting but of normal strength. Phenotype resembles that caused by killing pharyngeal M3 neurons, but is stronger. Lacks M3-derived IPSPs. | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001221 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | exhibits the Not phenotype | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001315 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Lacks M3-derived IPSPs. | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0003754 | PATO:0000460 | Person_evidence | WBPerson261 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0002056 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | weak Eat. Normal pumps are interspersed with abnormal pumps in which corpus contractions are feeble but long-lasting, and terminal bulb contractions are long-lasting but of normal strength. Phenotype resembles that caused by killing pharyngeal M3 neurons, but is stronger. Lacks M3-derived IPSPs. Other behavioral defects: Not, Fab,Che, Ttx; possibly general defect in glutametergic neurons | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Reference | WBPaper00014716 | ||||||||
| WBPaper00001709 | |||||||||
| WBPaper00036766 | |||||||||
| WBPaper00022174 | |||||||||
| Method | Allele |
