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WormBase Tree Display for Transgene: WBTransgene00006678

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Name Class

WBTransgene00006678Public_namemuEx14
Summary[Phsp16.1::mab-5, unc-31(+)]
ConstructionConstructWBCnstr00006521
Coinjection_otherunc-31
Construction_summaryThe extrachromosomal array muEx14 carries the hsp16.1-mab-5 construct and was obtained using the cotransformation marker unc-31 (cosmid C14G10; R. Hoskins, personal communication) (Salser and Kenyon 1992).
Genetic_informationExtrachromosomal
PhenotypeWBPhenotype:0000469Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
RemarkQR descendants aberrantly migrate to the posterior of the animal, similar to QL descendants (Figure 1); "To test whether mab-5 would also be sufficient to make the QR descendants stay in the posterior, we expressed mab-5 under the control of a C. elegans heat-shock promoter in a mab-5(lf) background (Fig. d). This produced a phenotype reciprocal to mab-5(lf) mutations: Q.a and Q.ap migrated posteriorly on both sides, whereas Q.p and its descendants simply stayed put as they normally do on the left side of the wild type."Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
Caused_by_geneWBGene00003102Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
Variation_effectGain_of_function_undetermined_typePaper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
EQ_annotationsAnatomy_termWBbt:0007279PATO:0000460Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
WBbt:0003927PATO:0000460Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
WBbt:0007281PATO:0000460Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
WBbt:0007282PATO:0000460Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
WBbt:0003832PATO:0000460Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
WBbt:0004991PATO:0000460Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
GO_termGO:0016477PATO:0000460Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
Phenotype_assayGenotypemab-5(e2088); unc-31(e169); him-5(e1490)Paper_evidenceWBPaper00001492
Curator_confirmedWBPerson2987
ReferenceWBPaper00001492
WBPaper00001798
SpeciesCaenorhabditis elegans