WormBase Tree Display for Transgene: WBTransgene00006678
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WBTransgene00006678 | Public_name | muEx14 | ||||||
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Summary | [Phsp16.1::mab-5, unc-31(+)] | |||||||
Construction | Construct | WBCnstr00006521 | ||||||
Coinjection_other | unc-31 | |||||||
Construction_summary | The extrachromosomal array muEx14 carries the hsp16.1-mab-5 construct and was obtained using the cotransformation marker unc-31 (cosmid C14G10; R. Hoskins, personal communication) (Salser and Kenyon 1992). | |||||||
Genetic_information | Extrachromosomal | |||||||
Phenotype | WBPhenotype:0000469 | Paper_evidence | WBPaper00001492 | |||||
Curator_confirmed | WBPerson2987 | |||||||
Remark | QR descendants aberrantly migrate to the posterior of the animal, similar to QL descendants (Figure 1); "To test whether mab-5 would also be sufficient to make the QR descendants stay in the posterior, we expressed mab-5 under the control of a C. elegans heat-shock promoter in a mab-5(lf) background (Fig. d). This produced a phenotype reciprocal to mab-5(lf) mutations: Q.a and Q.ap migrated posteriorly on both sides, whereas Q.p and its descendants simply stayed put as they normally do on the left side of the wild type." | Paper_evidence | WBPaper00001492 | |||||
Curator_confirmed | WBPerson2987 | |||||||
Caused_by_gene | WBGene00003102 | Paper_evidence | WBPaper00001492 | |||||
Curator_confirmed | WBPerson2987 | |||||||
Variation_effect | Gain_of_function_undetermined_type | Paper_evidence | WBPaper00001492 | |||||
Curator_confirmed | WBPerson2987 | |||||||
EQ_annotations (2) | ||||||||
Phenotype_assay | Genotype | mab-5(e2088); unc-31(e169); him-5(e1490) | Paper_evidence | WBPaper00001492 | ||||
Curator_confirmed | WBPerson2987 | |||||||
Reference | WBPaper00001492 | |||||||
WBPaper00001798 | ||||||||
Species | Caenorhabditis elegans |