WormBase Tree Display for RNAi: WBRNAi00110083
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| WBRNAi00110083 | Homol | Homol_homol | ZC376:RNAi | |||
|---|---|---|---|---|---|---|
| Sequence_info | PCR_product | mv_ZC376.7 | ||||
| Experiment | Genotype | eri-1(mg366) | ||||
| Delivered_by | Bacterial_feeding | |||||
| Inhibits | Predicted_gene | ZC376.7d | Inferred_automatically | RNAi_primary | ||
| ZC376.7b | Inferred_automatically | RNAi_primary | ||||
| ZC376.7a | Inferred_automatically | RNAi_primary | ||||
| ZC376.7c | Inferred_automatically | RNAi_primary | ||||
| Gene | WBGene00013878 | Inferred_automatically | RNAi_primary | |||
| Transcript | ZC376.7d.1 | Inferred_automatically | RNAi_primary | |||
| ZC376.7c.1 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7a.2 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7b.2 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7a.1 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7c.2 | Inferred_automatically | RNAi_primary | ||||
| ZC376.7b.1 | Inferred_automatically | RNAi_primary | ||||
| Species | Caenorhabditis elegans | |||||
| Reference | WBPaper00045829 | |||||
| Phenotype | WBPhenotype:0001013 | Remark | "Consistent with a role for ATFS-1 in inducing innate immune and mitochondrial protective genes5, the survival of worms raised on atfs- 1(RNAi) was significantly reduced when exposed to P. aeruginosa, but not E. coli (Fig. 3a, b). atfs-1(RNAi) treated worms were also susceptible to P. aeruginosa liquid-killing (Extended Data Fig. 2c), supporting a role for ATFS-1 in activating a protective transcriptional response to pathogen exposure." | |||
| EQ_annotations | GO_term | GO:0045087 | PATO:0000460 | |||
| Remark | (Figure 3a,3b, Extended Data Fig. 2c) atfs-1 RNAi | |||||
| Method | RNAi |
