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WormBase Tree Display for RNAi: WBRNAi00095097

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Name Class

WBRNAi00095097HomolHomol_homolF53G12:RNAi
F56C11:RNAi
Sequence_infoPCR_productsjj_F56C11.1
ExperimentLaboratoryGF
Date08 Aug 2009 00:00:00
StrainWBStrain00029103
TreatmentThe RNAi bacteria was mixed with a vector control at a ratio of 1 to 10 to reduce the severity of the blistered phenotype enough to enable development. Animals were feed RNAi bacteria and then and exposed to E. faecalis.
Delivered_byBacterial_feeding
InhibitsPredicted_geneF53G12.3Inferred_automaticallyRNAi_primary
F56C11.1Inferred_automaticallyRNAi_primary
GeneWBGene00018771Inferred_automaticallyRNAi_primary
WBGene00000253Inferred_automaticallyRNAi_primary
TranscriptF56C11.1.1Inferred_automaticallyRNAi_primary
F53G12.3.1Inferred_automaticallyRNAi_primary
F56C11.1.2Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00035115
PhenotypeWBPhenotype:0001013RemarkHypodermis-specific RNAi of bli-3 caused increased susceptibility to infection and higher relative mortality.
WBPhenotype:0001271RemarkHypodermis-specific RNAi of bli-3 caused increased susceptibility to infection and higher relative mortality.
RemarkHypodermis-specific RNAi of bli-3. In strain NR222 rde-1 is under the expression of a hypodermis-specific promoter in the rde-1(ne219) mutant background. An rde-1 mutation renders the RNAi machinery inactive and the worm is not susceptible to RNAi. However, when this gene is expressed under the control of a tissue-specific promoter, RNAi can then occur in these specific tissues.
MethodRNAi