WormBase Tree Display for RNAi: WBRNAi00078382
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| WBRNAi00078382 | Homol | Homol_homol | T22A3:RNAi | ||
|---|---|---|---|---|---|
| Sequence_info | PCR_product | sjj_T22A3.5 | |||
| Experiment | Laboratory | CK | |||
| Date | 16 Mar 2006 00:00:00 | ||||
| Genotype | aex-3::tau (FTDP-17 mutant human tau); myo-2::GFP | ||||
| Treatment | The FTDP-17 mutant human tau used in the transgene for this experiment contains a V337M change with its expression driven by the pan-neuronal promoter aex-3. The animals containing this transgene have what is called a tau-induced Unc phenotype. | ||||
| Delivered_by | Bacterial_feeding | ||||
| Inhibits | Predicted_gene | T22A3.5b | Inferred_automatically | RNAi_primary | |
| T22A3.5a | Inferred_automatically | RNAi_primary | |||
| Gene | WBGene00011908 | Inferred_automatically | RNAi_primary | ||
| Transcript | T22A3.5b.1 | Inferred_automatically | RNAi_primary | ||
| T22A3.5a.1 | Inferred_automatically | RNAi_primary | |||
| Species | Caenorhabditis elegans | ||||
| Interaction | WBInteraction000050732 | ||||
| Reference | WBPaper00027214 | ||||
| Phenotype | WBPhenotype:0000643 | Remark | This RNAi enhanced the tau-induced uncoordinated (Unc) phenotype (caused by the expression of mutant human tau -FTDP-17) as well as the Unc phenotype some/all of the four Unc lines tested (unc-3, unc-76, unc-78 and unc-87). | ||
| Method | RNAi |
