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WormBase Tree Display for RNAi: WBRNAi00078326

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Name Class

WBRNAi00078326HomolHomol_homolR74:RNAi
Sequence_infoPCR_productsjj_R74.3
ExperimentLaboratoryCK
Date16 Mar 2006 00:00:00
Genotypeaex-3::tau (FTDP-17 mutant human tau); myo-2::GFP
TreatmentThe FTDP-17 mutant human tau used in the transgene for this experiment contains a V337M change with its expression driven by the pan-neuronal promoter aex-3. The animals containing this transgene have what is called a tau-induced Unc phenotype.
Delivered_byBacterial_feeding
InhibitsPredicted_geneR74.3Inferred_automaticallyRNAi_primary
GeneWBGene00006959Inferred_automaticallyRNAi_primary
TranscriptR74.3.1Inferred_automaticallyRNAi_primary
R74.3.2Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000050676
ReferenceWBPaper00027214
PhenotypeWBPhenotype:0000643RemarkThis RNAi only enhanced the tau-induced uncoordinated (Unc) phenotype (caused by the expression of mutant human tau -FTDP-17) and not the Unc phenotype of the other four Unc lines tested (unc-3, unc-76, unc-78 and unc-87).
MethodRNAi