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WormBase Tree Display for RNAi: WBRNAi00022926

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Name Class

WBRNAi00022926History_name[cgc5264]:sep-1
HomolHomol_homolY47G6A:RNAi
Sequence_infoPCR_product[cgc4997]:sep-1
ExperimentLaboratoryMG
Date03 Apr 2002 00:00:00
StrainWBStrain00000001
InhibitsPredicted_geneY47G6A.12Inferred_automaticallyRNAi_primary
GeneWBGene00004775Inferred_automaticallyRNAi_primary
TranscriptY47G6A.12.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00005264
PhenotypeWBPhenotype:0001041RemarkIn embryos depleted of both GLC-7 and SEP-1 activity, during the first meiotic division, chromatid separation was greatly inhibited; the chromatin became somewhat dispersed, and individual chromosomes could occasionally be observed, but they never fully separate from the reainder of the chromatin as is the case when GLC-7 alone is depleted. glc-7alpha and glc-7beta were simultaneously depleted as well.
RemarkGFP-histone H2B was used to visualize the chromatin
MethodRNAi