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| WBPicture0000008500 | Description | Figure 4. Expression patterns of the unc-73 isoforms. The patterns of expression of the unc-73 isoforms B through F were determined using constructs that each specifically encode an individual unc-73 isoform tagged with GFP at the C terminus. The constructs were injected into wild-type animals, and the larvae and adults of the resulting stable lines were examined. All animals are oriented with the posterior to the left and anterior to the right. (A) UNC-73 B is strongly expressed in the axons of neurons. A cross-sectional side view of a late-larval stage animal reveals the nerve ring as two bright patches of fluorescence around the pharynx (arrowheads). (B) Expression of D1 driven by the myo-2 promoter in [myo-2p::D1::GFP] ev802/unc-11 dpy-5 animals is limited to the muscles of the pharynx. The C1 isoform is expressed in a limited set of neurons in the midbody of the animal (C) and the head (D). Arrowheads indicate the ventral cord. Also visible in the head are the neuronal support socket and/or sheath cells. The C2/F isoform has the same pattern of expression as C1. (E) D1 expression in the muscles of the pharynx and two neurons in the head. A few unidentified axons are faintly visible in a cross-section of the nerve ring (arrowheads). (F) The processes of D1-expressing neurons are visible in the ventral cord. The muscles of the vulva seen in the shape of an X, and the HSNR cell body (arrowhead) also express D1. The D2 isoform has the same pattern of expression as D1. (G) UNC-73 E is expressed in the axons and cell bodies of most if not all neurons and the excretory canals. The bright region in the head is a result of expression in axons of the nerve ring and the cell bodies of neurons in the ganglia surrounding the nerve ring. | |||
|---|---|---|---|---|---|
| Name | F4.large.jpg | ||||
| Depict | Expr_pattern | Expr3776 | |||
| Anatomy | WBbt:0003679 | ||||
| WBbt:0004757 | |||||
| WBbt:0005451 | |||||
| WBbt:0005750 | |||||
| WBbt:0005775 | |||||
| WBbt:0005811 | |||||
| WBbt:0005821 | |||||
| WBbt:0005829 | |||||
| WBbt:0006749 | |||||
| Cellular_component | GO:0030424 | ||||
| GO:0043025 | |||||
| Acknowledgment | Template | WormBase wishes to thank <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Journal_URL>, <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>. | |||
| Publication_year | 2005 | ||||
| Article_URL | DOI | id | 10.1101/gad.1319905 | ||
| Journal_URL | Genes&Development | ||||
| Publisher_URL | ColdSpringHarborLabPress | ||||
| Reference | WBPaper00026785 |
