WormBase Tree Display for Expr_pattern: Expr3776
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| Expr3776 | Expression_of | Gene | WBGene00006805 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006805 | ||
| Expression_data | Anatomy_term (34) | ||
| GO_term | GO:0030424 | ||
| GO:0043025 | |||
| Subcellular_localization | Expressed in axons and cell bodies. | ||
| Type | Reporter_gene | ||
| Pattern | In contrast, D1 and D2 were very strongly expressed in the muscles of the pharynx and vulva and in both the cell bodies and axons of a very restricted set of neurons. These included the hermaphrodite-specific neurons (HSNs), about four unidentified neurons with cell bodies in either the ventral or retrovesicular ganglion near the terminal bulb of the pharynx, and about six neurons with cell bodies in the lumbar ganglion in the tail, including PVQL and PVQR, as distinguished by their axonal patterning. A small number of axons were present in the nerve ring and the ventral cord. The lateral processes of ALNL and ALNR were also visible. D1 and D2 also exhibited sporadic and weak fluorescence in body wall and intestinal muscles. Isoform E was strongly expressed in the nervous system and was detected in the cell bodies and axons of most, if not all neurons, including those in the pharynx, and at least some of the neuron-associated sheath and/or socket cells. Isoform E was also observed in the excretory canals and the somatic gonad, including the spermatheca, gonadal sheath, and distal tip cells. | ||
| Isoform B was expressed most strongly in the axons of neurons, particularly in the nerve ring and the ventral nerve cord. This pattern of expression was very similar to the staining pattern observed with UNC-73 B antibodies. UNC-73 B was also found more sporadically and at a lower level in anal depressor muscle, distal tip, P, seam, and developing vulva cells. Although C1 and C2/F were also expressed in axons, their expression was restricted to fewer neurons. Many process bundles within the body of the animal and neurons within the pharynx were positive for C1 and C2/F, but few axons were visible in the nerve ring. Along with the neuronal expression, C1 and C2/F were also expressed in neuron-associated socket and/or sheath cells and the neuroendocrine uv1 cells. A low level of expression was sporadically observed in body wall muscles. | |||
| Picture | WBPicture0000008500 | ||
| Reference | WBPaper00026785 | ||
| Transgene | WBTransgene00028868 |
