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WBPicture0000007523DescriptionGFP::RAC-2 is anchored to the plasma membrane. The unc-115::gfp::rac-2 transgene is predicted to produce a RAC-2 molecule with an N-terminal GFP tag. The CAAX motif at the C terminus of RAC-2 might direct covalent addition of a prenyl group and subsequent anchorage of the molecule to the plasma membrane. (B,D) Wild-type animals harboring the unc-115::gfp::rac-2 transgene. GFP::RAC-2 accumulated at the cell margins of neuroblasts of the 1.5-fold embryo in (B) and of neurons in the L1 larva in C. The animal in C displayed strong GFP::RAC-2 accumulation in the nerve ring. (D) A magnified image of the area around the nerve ring of the animal in (C). Neuron cell bodies with GFP::RAC-2 at their periphery are evident. Scale bars: in B 10 um for B,C; in D 2 um.
NameF3.large_BD.jpg
CropCropped_fromWBPicture0000007522
DepictExpr_patternExpr2278
AnatomyWBbt:0003679
WBbt:0006749
Cellular_componentGO:0005886
GO:0030424
AcknowledgmentTemplateWormBase thanks <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>.
Publication_year2003
Article_URLDOIid10.1242/dev.00300
Journal_URLDevelopment
Publisher_URLTheCompanyofBiologists
ReferenceWBPaper00005607