WormBase Tree Display for Interaction: WBInteraction000571509
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| WBInteraction000571509 | Interaction_type | Genetic | Partial_suppression | ||
|---|---|---|---|---|---|
| GI_module_two | Sub_suppressing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00000417 | Interactor_type | Effector | |
| Other_interactor | Expression of hepatitis B virus protein HBx in touch cells | Interactor_type | Affected | ||
| Variation_interactor | WBVar00090474 | Interactor_type | Effector | ||
| Interaction_summary | "Consistently, cell killing by HBx was partially suppressed by either ced-3(n2433) or mec-6(e1342) lf mutations and eliminated by loss of both genes (Fig. 2A). These results confirm that HBx induces both apoptosis and necrosis in C. elegans." "Loss of egl-1, ced-3, or ced-4 partially suppressed HBx-induced cell death (from 50% to 22-26% PLM death; Fig. 2A), indicating that HBx induces cell death partly through the apoptotic pathway." | ||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0000183 | ||||
| Unaffiliated_transgene | WBTransgene00015954 | ||||
| WBProcess | WBbiopr:00000014 | ||||
| Paper | WBPaper00041673 | ||||
| Remark | Figure 2A |
