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WormBase Tree Display for Interaction: WBInteraction000560298

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Name Class

WBInteraction000560298Interaction_typePhysicalProteinProtein
InteractorInteractor_overlapping_geneWBGene00006750Interactor_typeBait
WBGene00006752Interactor_typeTarget
Interaction_summary"UNC-13L C2A domain tightly binds the UNC-10/RIM ZF domain, and that this interaction was eliminated by a double mutation in the ZF domain (K77/79E), which is analogous to mutations that disrupt binding of the corresponding mammalian Munc13-1 and RIM domains"
Detection_methodReconstituted_complex
ThroughputLow_throughput
PaperWBPaper00056288
Remarkfig. 1, isothermal titration calorimetry (ITC) used.