WormBase Tree Display for Interaction: WBInteraction000560298
expand all nodes | collapse all nodes | view schema
WBInteraction000560298 | Interaction_type | Physical | ProteinProtein | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene | WBGene00006750 | Interactor_type | Bait | |
WBGene00006752 | Interactor_type | Target | |||
Interaction_summary | "UNC-13L C2A domain tightly binds the UNC-10/RIM ZF domain, and that this interaction was eliminated by a double mutation in the ZF domain (K77/79E), which is analogous to mutations that disrupt binding of the corresponding mammalian Munc13-1 and RIM domains" | ||||
Detection_method | Reconstituted_complex | ||||
Throughput | Low_throughput | ||||
Paper | WBPaper00056288 | ||||
Remark | fig. 1, isothermal titration calorimetry (ITC) used. |