WormBase Tree Display for Interaction: WBInteraction000558227
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| WBInteraction000558227 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001612 | Interactor_type | Trans_regulator | |
| Other_interactor | heat shock | Interactor_type | Trans_regulator | ||
| Interaction_summary | "we tested whether the heat shock would alter the effect of training on the expression of GLR-1::GFP. We found that, 24 hr after training, the mean length of GLR-1::GFP clusters in worms that received heat shock (32C for 40 min after each training block) during distributed habituation training on day 1 did not differ from worms that received only a single tap on day 1 (trained with heat shock, n = 18, x = 496.95 +/- 50.2; control with heat shock, n = 16, x = 468.75 +/- 54.26; t(31) = 0.380; p = 0.71). In contrast, worms that received distributed training with sham heat shock (21C for 40 min after each training block) showed decreased mean length of GLR-1::GFP clusters 24 hr after training when compared with their single-tap controls (trained with sham shock, n = 18, x = 374.8 +/- 26.38; control with sham shock, n = 18, x = 485.26 +/- 33.47; t(34) = 2.6; p = 0.01). Thus, heat shock blocked the alteration in GLR-1::GFP expression usually seen after distributed habituation training, without affecting any other aspect of GLR-1::GFP expression (compare GLR-1::GFP levels in control heat shock and sham shock groups)." | ||||
| Detection_method | Reporter_gene | [GLR-1::GFP] | |||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0005829 | ||
| Subcellular_localization | synapse | ||||
| Paper | WBPaper00006159 |
