WormBase Tree Display for Interaction: WBInteraction000558131
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| WBInteraction000558131 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001752 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00000413 | ||||
| Construct | WBCnstr00000413 | ||||
| Other_interactor | XOD | Interactor_type | Trans_regulator | ||
| Interaction_summary | "In BL1 C. elegans, a 1000 bp Ce-GSTp24 promoter region controls the expression of the Ce-GST-p24-GFP fusion protein (Fig. 1A). In response to oxidative stress, a significant increase of the promoter activity in the CL2166 and BL1 C. elegans was observed by photometric measurement of the GFP fluorescence (Fig. 1B). In response to 200 uM plumbagin and 100 mM paraquat, the promoter activity in CL2166 and BL1 worms was 2- to 3-fold higher than in unstressed control animals. In worms stressed with 200 uM juglone, the activity reached 4.3-fold (CL2166) and 6.5-fold (BL1) as compared to control worms. Externally generated ROS by the hypoxanthine/XOD system, UV light, and heat shock did not have a stimulating effect on the Ce-GST-p24 promoter (Fig. 1B)." | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [gst-4p::gfp] | ||||
| Transgene | |||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00005888 | ||||
| Remark | Fig. 1b; 100mU/mL XOD |
