WormBase Tree Display for Interaction: WBInteraction000558063
expand all nodes | collapse all nodes | view schema
| WBInteraction000558063 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00006784 | Interactor_type | Trans_regulated | |
| Expr_pattern | Marker2 | ||||
| Transgene | WBTransgene00000786 | ||||
| Construct | WBCnstr00020010 | ||||
| WBGene00006831 | Interactor_type | Trans_regulator | |||
| WBGene00001862 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00143865 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "we analyzed GABA receptor clusters in unc-104 mutants... we could not detect any SNB-1-CFP in the dorsal nerve cord of unc-104(e1265) mutants (Fig. 5A)... In these animals, a faint and diffuse UNC-49-YFP signal was observed in dorsal muscle cells, but no clusters were present along the dorsal cord (Fig. 5B). Furthermore, along the ventral side of the unc-104(e1265) mutants, unusually large and irregular UNC-49-YFP aggregates were found along the ventral cord where residual numbers of synaptic vesicles accumulated (Fig. 5C). UNC-49-YFP clusters were also found directly in contact with the cell bodies of the GABA motor neurons (Fig. 5C, inset)." | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [UNC-49::YFP] | ||||
| Transgene | |||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0008389 | ||
| Paper | WBPaper00005798 | ||||
| Remark | Fig. 5b |
