WormBase Tree Display for Interaction: WBInteraction000558062
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| WBInteraction000558062 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00006831 | Interactor_type | Trans_regulator | |
| WBGene00004897 | Interactor_type | Trans_regulated | |||
| WBGene00001862 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00143865 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "we analyzed GABA receptor clusters in unc-104 mutants... we could not detect any SNB-1-CFP in the dorsal nerve cord of unc-104(e1265) mutants (Fig. 5A)... In these animals, a faint and diffuse UNC-49-YFP signal was observed in dorsal muscle cells, but no clusters were present along the dorsal cord (Fig. 5B). Furthermore, along the ventral side of the unc-104(e1265) mutants, unusually large and irregular UNC-49-YFP aggregates were found along the ventral cord where residual numbers of synaptic vesicles accumulated (Fig. 5C). UNC-49-YFP clusters were also found directly in contact with the cell bodies of the GABA motor neurons (Fig. 5C, inset)." | ||||
| Detection_method | Reporter_gene | [SNB-1::CFP] | |||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0006750 | ||
| Subcellular_localization | axons | ||||
| Paper | WBPaper00005798 | ||||
| Remark | Fig. 5a |
