WormBase Tree Display for Interaction: WBInteraction000557575
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| WBInteraction000557575 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003931 | Interactor_type | Trans_regulator | |
| WBGene00000942 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00248762 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "In wild-type embryos 430 min postfertilization, the dense body protein DEB-1/vinculin has already polarized to the basal sarcolemma and is organized into nascent attachments that appear as a continuous stripe of staining along each muscle quadrant (Figure 4E)... DEB-1/vinculin polarizes within the pat-4 embryos but does not appear to fully assemble into nascent attachments (Figure 4F), as indicated by the different integrin and DEB-1/vinculin localization in pat-4 mutants (compare arrows in Figures 4D and 4F)." | ||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000003 | ||
| Anatomy_term | WBbt:0005737 | ||||
| Subcellular_localization | longitudinal stripe | ||||
| Paper | WBPaper00005261 | ||||
| Antibody_remark | anti-DEB-1 | ||||
| Remark | Fig. 4 |
