WormBase Tree Display for Interaction: WBInteraction000557545
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| WBInteraction000557545 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00000934 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00004906 | ||||
| Construct | WBCnstr00004887 | ||||
| Molecule_interactor | WBMol:00004561 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "Coexposure of worms with 6-OHDA and imipramine (Fig. 2 d and f ) or nisoxetine (data not shown) dramatically reduced the loss of GFP expression seen with 6-OHDA alone. The sensitivity of the toxin to the dopamine neurons was also blocked by the psychoactive analog D-amphetamine (Fig. 2f )." | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [dat-1::GFP] | ||||
| Transgene | |||||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0003679 | ||
| Paper | WBPaper00005147 | ||||
| Remark | Fig. 2f |
