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WormBase Tree Display for Interaction: WBInteraction000557093

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Name Class

WBInteraction000557093Interaction_typeRegulatoryChange_of_localization
InteractorInteractor_overlapping_geneWBGene00000100Interactor_typeTrans_regulated
TransgeneWBTransgene00000673
ConstructWBCnstr00000670
WBGene00001006Interactor_typeTrans_regulator
Interaction_summary"We performed DLG-1 RNAi on nematodes that express AJM-1::GFP and found that dlg-1(RNAi) embryos do not form junctions of AJM-1 around the apex of cells even at the earliest developmental stages at which AJM-1::GFP can be detected (Figure 2G, n = 32/36, and our unpublished results). In most dlg-1(RNAi) animals, AJM-1::GFP is found in small punctate structures between cells (Figure 2G, n = 32/36) rather than showing a continuous ring of localization at cell boundaries as in wild-type embryos (Figure 2A,D, n 22/22)."
Detection_methodConstruct
Reporter_gene[AJM-1::GFP]
Transgene
Regulation_levelPost_translational
Regulation_resultPositive_regulateLife_stageWBls:0000003
Subcellular_localizationcell boundaries
PaperWBPaper00004983
RemarkFig. 2