WormBase Tree Display for Gene: WBGene00000100
expand all nodes | collapse all nodes | view schema
| WBGene00000100 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | ajm-1 | Person_evidence | WBPerson240 | |||||
| Sequence_name | C25A11.4 | ||||||||
| Molecular_name (42) | |||||||||
| Other_name | jam-1 | ||||||||
| H08J11.c | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| H08J11.a | |||||||||
| H08J11.b | |||||||||
| CELE_C25A11.4 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | ajm-1 | ||||||||
| DB_info | Database | AceView | gene | XJ731 | |||||
| WormQTL | gene | WBGene00000100 | |||||||
| WormFlux | gene | WBGene00000100 | |||||||
| NDB | locus_tag | CELE_C25A11.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000100|UniProtKB=A0A1C3NSL9 | |||||||
| family | PTHR21517 | ||||||||
| NCBI | gene | 181148 | |||||||
| RefSeq | protein (13) | ||||||||
| SwissProt | UniProtAcc | A0A1C3NSL9 | |||||||
| TrEMBL | UniProtAcc | H2KYC5 | |||||||
| Q95ZY7 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A1C3NSL9 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 01 Jul 2016 14:56:15 | WBPerson1983 | Event | Acquires_merge | WBGene00044785 | ||||
| 3 | 01 Jul 2016 14:56:15 | WBPerson1983 | Event | Acquires_merge | WBGene00019173 | ||||
| Acquires_merge | WBGene00044785 | ||||||||
| WBGene00019173 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ajm | ||||||||
| Allele (507) | |||||||||
| Legacy_information | [Raich WB, Hardin JD] No mutants known. Encodes protein recognized by monoclonal antibody MH27, associated with apical cell-cell junctions. Predicted gene C25A11.4 + C25A11.3 | ||||||||
| Strain (22) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Ortholog (27) | |||||||||
| Structured_description | Concise_description | ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. | Paper_evidence | WBPaper00004765 | |||||
| WBPaper00004961 | |||||||||
| WBPaper00005194 | |||||||||
| WBPaper00005946 | |||||||||
| WBPaper00005969 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable cytoskeletal protein binding activity. Involved in cell-cell junction organization and embryo development. Located in apicolateral plasma membrane; cell-cell junction; and plasma membrane bounded cell projection. Expressed in several structures, including arcade cell and epithelial cell. Is an ortholog of human AJM1 (apical junction component 1 homolog). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS (13) | ||||||||
| Corresponding_CDS_history | C25A11.4b:wp254 | ||||||||
| C25A11.4c:wp254 | |||||||||
| C25A11.4d:wp254 | |||||||||
| C25A11.4e:wp254 | |||||||||
| Corresponding_transcript (16) | |||||||||
| Other_sequence (84) | |||||||||
| Associated_feature (76) | |||||||||
| Experimental_info | RNAi_result (26) | ||||||||
| Expr_pattern (20) | |||||||||
| Drives_construct (23) | |||||||||
| Construct_product (11) | |||||||||
| Antibody | WBAntibody00000055 | ||||||||
| WBAntibody00001322 | |||||||||
| Microarray_results (94) | |||||||||
| Expression_cluster (304) | |||||||||
| Interaction (104) | |||||||||
| Map_info | Map | X | Position | 0.672056 | Error | 0.047992 | |||
| Positive | Positive_clone | C25A11 | Person_evidence | WBPerson506 | |||||
| Author_evidence | Hardin JD | ||||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 4150 | |||||||
| Pseudo_map_position | |||||||||
| Reference (133) | |||||||||
| Remark | .3 gene was merged with .4 gene | ||||||||
| Sequence connection from [Koppen M, Hardin JD] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
