WormBase Tree Display for Interaction: WBInteraction000557072
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| WBInteraction000557072 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003992 | Interactor_type | Trans_regulator | |
| WBGene00002059 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00054562 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "In 99% of the pgl-1 embryos examined (n>160), IFE-1::GFP signal was not detectably associated with P granules but was still present in the cytoplasm (compare Fig. 5E,5H). Co-staining embryos with anti-GFP and anti-GLH-2 antibodies confirmed that pgl-1 mutants contain P granules but that those P granules lack detectable IFE-1::GFP (Fig. 5F,G). These results suggest that PGL-1 is required for IFE-1 localization to P granules in wildtype animals." | ||||
| Detection_method | Reporter_gene | [IFE-1::GFP] | |||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000003 | ||
| Subcellular_localization | P granules | ||||
| Paper | WBPaper00004940 | ||||
| Remark | Fig. 5 |
