WormBase Tree Display for Interaction: WBInteraction000549911

WBInteraction000549911 Interaction_type: Regulatory: Change_of_expression_level
  Interactor: Interactor_overlapping_gene: WBGene00003999 Interactor_type: Trans_regulated
        Transgene: WBTransgene00000017
        Construct: WBCnstr00000017
      WBGene00012124 Interactor_type: Trans_regulator
  Interaction_summary: "A genome-wide RNAi screen identified 170 gene inactivations that disrupt pgp-5::gfp response to G418 (Supplementary Table 8). We tested the 170 primary screen candidate gene inactivations in duplicate for disruption of pgp-5::gfp induction in eft-3(q145) homozygous animals (Supplementary Table 9); 71 gene inactivations also disrupted normal pgp-5::gfp induction in response to a germline translation defect (Supplementary Table 9 and Fig. 4c-e). Inactivation of many of the genes from the RNAi screen caused hypersensitivity to G418 or hygromycin (Supplementary Fig. 2g and Fig. 4f,g),"
  Detection_method: Construct
    Reporter_gene: [pgp-5::gfp]
    Transgene
  Regulation_result: Positive_regulate: Life_stage: WBls:0000109
  Paper: WBPaper00048491
  Remark: Table S9