WormBase Tree Display for Interaction: WBInteraction000549854
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WBInteraction000549854 | Interaction_type | Regulatory | Change_of_expression_level | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene | WBGene00003999 | Interactor_type | Trans_regulated | |
Transgene | WBTransgene00000017 | ||||
Construct | WBCnstr00000017 | ||||
WBGene00001994 | Interactor_type | Trans_regulator | |||
Interaction_summary | "To identify the signalling components that are required for induction of pgp-5::gfp or gst-4::gfp in the intestine in response to the iff-1(tm483) or rpl-11.1(ar228) germline-translation-defective mutations, we screened a 450-gene kinase and 600-gene transcription factor RNAi library (Methods and Supplementary Tables 4 and 5). Positive hits from the screen were rescreened on the eft-3(q145);pgp-5::gfp germline-translation-defective strain, and most were required for pgp-5::gfp induction in eft-3(q145) (Fig. 3a,b)." | ||||
Detection_method | Construct | ||||
Reporter_gene | [pgp-5::gfp] | ||||
Transgene | |||||
Regulation_result | Negative_regulate | Life_stage | WBls:0000041 | ||
Paper | WBPaper00048491 | ||||
Remark | Fig. 3b |