WormBase Tree Display for Interaction: WBInteraction000549476
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| WBInteraction000549476 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001194 | Interactor_type | Trans_regulator | |
| WBGene00019660 | Interactor_type | Trans_regulated | |||
| WBGene00018138 | Interactor_type | Trans_regulated | |||
| WBGene00010125 | Interactor_type | Trans_regulated | |||
| WBGene00007153 | Interactor_type | Trans_regulated | |||
| WBGene00009971 | Interactor_type | Trans_regulated | |||
| WBGene00011979 | Interactor_type | Trans_regulated | |||
| WBGene00022645 | Interactor_type | Trans_regulated | |||
| WBGene00015449 | Interactor_type | Trans_regulated | |||
| WBGene00009432 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00089296 | Interactor_type | Trans_regulator | ||
| WBVar00092878 | Interactor_type | Trans_regulator | |||
| Interaction_summary | "Out of 22 tested DAF-16 target genes 12 showed significantly diminished induction following UV irradiation in egl-27 mutants when compared with WT (Fig. 6a), indicating that EGL-27 regulates a subset of DAF-16-dependent DNA-damage-response genes. Among those, RNA-mediated interference (RNAi) against the DNA damage effector downstream of DAF-16 and EGL-27' (dde) genes dde-1 (F01D5.1) and dde-2 (F01D5.2), as well as a mutation in oac-32, which we renamed dde-3, significantly enhanced developmental arrest following UV treatment (Fig. 6b)." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000106 | ||
| Paper | WBPaper00047070 | ||||
| Remark | Fig. 6a |
