WormBase Tree Display for Interaction: WBInteraction000549474
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WBInteraction000549474 | Interaction_type | Regulatory | Change_of_localization | |
---|---|---|---|---|
Interactor | Interactor_overlapping_gene (2) | |||
Interaction_summary | "Although in the absence of UV DAF-16::GFP was completely cytoplasmic, we observed a transient nuclear localization following UV treatment during larval stages (L1 larvae Fig. 1c; L3 larvae Supplementary Fig. 1G). DAF-16 showed nearly complete and prolonged nuclear localization in completely NER- and TC-NER-deficient mutants following UV damage, whereas GG-NER-defective worms behaved similarly to WT animals (Fig. 1c and Supplementary Fig. 1G), suggesting that transcription-blocking lesions lead to activation of DAF-16." | |||
Detection_method | Construct | |||
Reporter_gene | [DAF-16::GFP] | |||
Transgene | ||||
Regulation_level | Post_translational | |||
Regulation_result | Negative_regulate | Life_stage | WBls:0000108 | |
Subcellular_localization | nucleus | |||
Paper | WBPaper00047070 | |||
Remark | Fig. S1g |