WormBase Tree Display for Interaction: WBInteraction000549474
expand all nodes | collapse all nodes | view schema
WBInteraction000549474 | Interaction_type | Regulatory | Change_of_localization |
---|---|---|---|
Interactor | Interactor_overlapping_gene (2) | ||
Interaction_summary | "Although in the absence of UV DAF-16::GFP was completely cytoplasmic, we observed a transient nuclear localization following UV treatment during larval stages (L1 larvae Fig. 1c; L3 larvae Supplementary Fig. 1G). DAF-16 showed nearly complete and prolonged nuclear localization in completely NER- and TC-NER-deficient mutants following UV damage, whereas GG-NER-defective worms behaved similarly to WT animals (Fig. 1c and Supplementary Fig. 1G), suggesting that transcription-blocking lesions lead to activation of DAF-16." | ||
Detection_method (3) | |||
Regulation_level | Post_translational | ||
Regulation_result | Negative_regulate (2) | ||
Paper | WBPaper00047070 | ||
Remark | Fig. S1g |