WormBase Tree Display for Interaction: WBInteraction000542946
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| WBInteraction000542946 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00000912 | Interactor_type | Trans_regulator | |
| WBGene00000190 | Interactor_type | Trans_regulated | |||
| WBGene00017625 | Interactor_type | Trans_regulated | |||
| WBGene00017501 | Interactor_type | Trans_regulated | |||
| WBGene00018707 | Interactor_type | Trans_regulated | |||
| Interaction_summary | "we compared transcript abundance by qPCR in heat shocked hs:: DNTbar- 1 animals and hs:: DNT-bar-1; daf-16(mgDf50) animals. We found that four of the 22 BAR-1 responsive genes (arf-1.1, cgt-2, F15E11.15, oac-31) were no longer strongly up-regulated by DNTBAR-1 in the absence of DAF-16 (Table 1)." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00044857 | ||||
| Remark | Table 1; "To conditionally activate Wnt signaling, we used hs::DNTbar-1, a transgene that uses the heat shock promoter to express a BAR-1 protein with an amino-terminal deletion (DNTBAR-1) predicted to stabilize the protein in the absence of Wnt signaling (Figure 1A) (Gleason et al. 2002)." |
