WormBase Tree Display for Interaction: WBInteraction000542026
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| WBInteraction000542026 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003854 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr282 | ||||
| Transgene | WBTransgene00000825 | ||||
| Construct | WBCnstr00000819 | ||||
| Antibody | WBAntibody00000417 | ||||
| WBGene00044330 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00095039 | Interactor_type | Trans_regulator | ||
| Interaction_summary | In alr-1 mutants, expression of the odr-7 nuclear receptor gene was lost in one or infrequently, in both AWA olfactory neurons. Ectopic expression of odr-7 in a second sensory neuron at a lower penetrance was also observed. | ||||
| Detection_method | Construct | ||||
| Antibody | |||||
| Reporter_gene | [odr-7::gfp], translational fusion | ||||
| Transgene | |||||
| In_situ | |||||
| Regulation_result | Negative_regulate | Anatomy_term | WBbt:0005664 | ||
| Paper | WBPaper00025052 | ||||
| Remark | A subset of ASG neurons adopt AWA-like characteristics in alr-1 mutants. Thus, ALR-1 appears to regulate the differentiation of both the AWA and ASG lineal sibling neurons, and moreover, ALR-1 acts to repress the AWA fate in a subset of ASG neurons. |
