WormBase Tree Display for Interaction: WBInteraction000536401
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| WBInteraction000536401 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00000222 | Interactor_type | Trans_regulator | |
| WBGene00008852 | Interactor_type | Trans_regulated | |||
| WBGene00022703 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00091838 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "In the control wild-type N2 worms, expression of ubiquilin and erasin transcripts increased after 6 h of tunicamycin treatment (Fig. 8). However, the induction of both genes was almost completely attenuated in ire-1(v33) mutant worms, and partially attenuated in the atf-6(ok551) and pek-1(ok275) mutants (Fig. 8). Together, these results indicate that in C. elegans, both ubiquilin and erasin genes are chiefly regulated by ire-1." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00035294 | ||||
| Remark | Figure 8 |
