WormBase Tree Display for Interaction: WBInteraction000524404
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| WBInteraction000524404 | Interaction_type | Genetic | Suppression | ||
|---|---|---|---|---|---|
| GI_module_two | Suppressing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00000393 | Interactor_type | Effector | |
| WBGene00002335 | Interactor_type | Affected | |||
| Variation_interactor | WBVar00090512 | Interactor_type | Effector | ||
| WBVar00089919 | Interactor_type | Affected | |||
| Interaction_summary | To investigate the cellular events that account for the suppression of Muv phenotype, authors used Nomarski optics to examine the fates of P3.p, P4.p, and P8.p. In let-60(n1046gf) single mutants, 37% of these cells adopted complete or partial vulval cell fates (n = 36). By contrast, in let-60(n1046gf); cdf-1(n2527) double mutants, P3.p, P4.p, and P8.p always adopted an uninduced tertiary cell fate (n = 36). Thus, the suppression of Muv phenotype caused by cdf-1 mutations is due to a transformation of vulval to nonvulval cell fates in P3.p, P4.p, and P8.p, and cdf-1 appears to regulate the initial step in Pn.p cell fate determination. | ||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0000414 | ||||
| WBProcess | WBbiopr:00000020 | ||||
| Paper | WBPaper00005255 |
